Recombinant Anti-Chl1 Vesicular Antibody, EV Displayed (VS-0425-YC754)
CAT#: VS-0425-YC754
The Recombinant Anti-Chl1 Vesicular Antibody, EV Displayed (VS-0425-YC754) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to Chl1-expressed cells or tissues. Chl1 is a cell adhesion molecule involved in neuron survival and behavior regulation, linked to schizophrenia and expressed in neural tissues.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26120/54553_B_8_5.jpg
Normal Tissue
Figure 2 Colon
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26120/54553_A_9_3.jpg
Normal Tissue
Figure 3 Kidney
Proximal tubules (cell body)
Staining: High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26120/54553_A_7_5.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (SK-MEL-30, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134121-CHL1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- Chl1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Cell adhesion molecule L1 like
- Biological Process
- Cell adhesion, Differentiation, Neurogenesis
- Molecular Function
- Developmental protein
- Introduction
- Enables protease binding activity. Involved in negative regulation of neuron apoptotic process. Acts upstream of or within several processes, including adult locomotory behavior; exploration behavior; and generation of neurons. Located in apical part of cell and dendrite. Is expressed in head mesenchyme; nervous system; and retina. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human CHL1 (cell adhesion molecule L1 like).
- Alternative Names
- A530023M13Rik, CALL, LICAM2
- Gene ID
- 12661
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "CHL1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-200 | Recombinant Anti-human CHL1 Antibody | ELISA, WB, FuncS | IgG |
| MHH-200 | Recombinant Human Anti-human CHL1 Antibody | IF, WB, FuncS | IgG |
| MOB-038LC | Rat Anti-CHL1 Recombinant Antibody (clone YC021) | WB | Rat IgG |
| CBPAB-045LC | Rabbit Anti-CHL1 Polyclonal Antibody | IHC, WB | Rabbit IgG |
| FAMAB-0065YC | Human Anti-CHL1 Recombinant Antibody (clone 6C2) | ELISA, IF, WB | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-200-F(E) | Recombinant Anti-human CHL1 Antibody Fab Fragment | WB, FuncS | Fab |
| MHH-200-F(E) | Recombinant Human Anti-human CHL1 Antibody Fab Fragment | WB, Neut, FuncS | Fab |
| FAMAB-0065-YC-F(E) | Human Anti-CHL1 Recombinant Antibody (clone 6C2); Fab Fragment | ELISA, IF, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-200-S(P) | Recombinant Anti-human CHL1 Antibody scFv Fragment | FC, ELISA, FuncS | scFv |
| MHH-200-S(P) | Recombinant Human Anti-human CHL1 Antibody scFv Fragment | FC, WB, FuncS | scFv |
| FAMAB-0065-YC-S(P) | Human Anti-CHL1 Recombinant Antibody (clone 6C2); scFv Fragment | ELISA, IF, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC29 | Rabbit Anti-CHL1 Antibody (VS-0924-YC29) - Cancer Stem Cell Marker | IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1440 | Anti-CHL1 Immunohistochemistry Kit | IHC |
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