Recombinant Anti-CHODL Vesicular Antibody, EV Displayed (VS-0425-YC30)
CAT#: VS-0425-YC30
The Recombinant Anti-CHODL Vesicular Antibody, EV Displayed (VS-0425-YC30) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CHODL-expressed cells or tissues. The CHODL is a type I membrane protein with a C-type lectin domain involved in glycoprotein endocytosis.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & centrosome.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57559/1981_C2_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line HDLM-2
Immunofluorescent staining of human cell line HDLM-2 shows localization to cytosol & centrosome.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57559/1959_B10_3_red_green.jpg
Normal Tissue
Figure 3 Testis
Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity:>75%
Preleptotene spermatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%
Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17282/156829_A_6_6.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (HDLM-2, U-266/70, U-266/84, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000154645-CHODL
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CHODL
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Chondrolectin
- Biological Process
- Neurogenesis
- Cellular Localization
- Cytosol, Centrosome
- Introduction
- This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. This protein localizes predominantly to the perinuclear region. Several transcript variants encoding a few different isoforms have been found for this gene.
- Alternative Names
- C21orf68, FLJ12627, MT75, PRED12
- Gene ID
- 140578
- UniProt ID
- Q9H9P2
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CHODL"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-1056 | Mouse Anti-CHODL Recombinant Antibody (clone YC022); Fab Fragment | LMNX, ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0696 | Hi-Affi™ Rabbit Anti-CHODL Recombinant Antibody (clone DS696AB) | WB, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0723-WK120 | Human Anti-CHODL Recombinant Antibody (VS-0723-WK120) | FC | Chimeric (rabbit/human) IgG1 |
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