Recombinant Anti-CLEC4A Vesicular Antibody, EV Displayed (VS-0425-YC726)
CAT#: VS-0425-YC726
The Recombinant Anti-CLEC4A Vesicular Antibody, EV Displayed (VS-0425-YC726) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CLEC4A-expressed cells or tissues. CLEC4A is a type 2 transmembrane protein in the C-type lectin superfamily, playing roles in inflammation and immune response.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7842/ihc_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (ASC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111729-CLEC4A
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CLEC4A
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- C-type lectin domain family 4 member A
- Biological Process
- Adaptive immunity, Host-virus interaction, Immunity, Innate immunity
- Introduction
- This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
- Alternative Names
- CD367, CLECSF6, DCIR, DDB27, hDCIR
- Gene ID
- 50856
- UniProt ID
- Q9UMR7
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CLEC4A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1856z-F(E) | Recombinant Anti-Human CLEC4A Antibody Fab Fragment | WB, Neut, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1856z-S(P) | Recombinant Anti-Human CLEC4A Antibody scFv Fragment | FC, RIA, Biosensors, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1112MZ | Recombinant Mouse Anti-Human CLEC4A Antibody (clone NN0348- 6Q30) | FC | Mouse antibody |
| FAMAB-1107CQ | Human Anti-CLEC4A Recombinant Antibody (clone 9E8) | FC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0128MZ | Chicken Anti-CLEC4A Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0722 | Hi-Affi™ Rabbit Anti-CLEC4A Recombinant Antibody (clone DS722AB) | ELISA, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1497 | Anti-CLEC4A Immunohistochemistry Kit | IHC |
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