Recombinant Anti-Cs Vesicular Antibody, EV Displayed (VS-0425-YC753)
CAT#: VS-0425-YC753
The Recombinant Anti-Cs Vesicular Antibody, EV Displayed (VS-0425-YC753) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to Cs-expressed cells or tissues. Cs is a citrate synthase, involved in metabolic pathways like the citric acid cycle, related to conditions like polyneuropathy.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38460/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38461/94883_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38461/94883_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38461/94883_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Bowman's capsule Staining: High Intensity: Strong Quantity:>75% Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Collecting ducts Staining: High Intensity: Strong Quantity:>75% Distal tubules Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38461/94883_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38461/94883_A_6_6.jpg
Normal Tissue
Figure 7 Heart muscle
Cardiomyocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38461/94883_B_4_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38461/94883_A_9_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000062485-CS
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- Cs
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Citrate synthase
- Biological Process
- Tricarboxylic acid cycle
- Molecular Function
- Transferase
- Cellular Localization
- Mitochondria
- Introduction
- CS (Citrate Synthase) is a Protein Coding gene. Diseases associated with CS include Critical Illness Polyneuropathy and Cat-Scratch Disease. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Pyruvate metabolism and Citric Acid (TCA) cycle. Gene Ontology (GO) annotations related to this gene include citrate (Si)-synthase activity.
- Gene ID
- 1431
- UniProt ID
- O75390
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Datasheet
MSDS
COA
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See other products for "CS"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1864z | Mouse Anti-CS Recombinant Antibody (clone 31C5) | WB, ICC, IF, IHC | Mouse IgG2a |
| FAMAB-0077YC | Mouse Anti-Cs Recombinant Antibody (clone R45-45-11) | ELISA | Mouse IgG1, κ |
| MRO-0364-CN | Rabbit Anti-CS Recombinant Antibody (clone JU80-30) | WB, IHC, FC | Rabbit IgG |
| VS3-XY533 | Mouse Anti-CS Recombinant Antibody (clone 1G1) | WB, IP, IF, IHC | Mouse IgG1 |
| VS13-YC254 | Rabbit Anti-CS Recombinant Antibody (VS13-YC254) | WB, IHC-Fr, IHC-P, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0822 | Hi-Affi™ Rabbit Anti-CS Recombinant Antibody (clone DS822AB) | WB, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0077-YC-S(P) | Mouse Anti-Cs Recombinant Antibody (clone R45-45-11); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0077-YC-F(E) | Mouse Anti-Cs Recombinant Antibody (clone R45-45-11); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1120 | AbPlus™ Anti-CS Magnetic Beads (VS-0724-YC1120) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY556 | Anti-CS Immunohistochemistry Kit | IHC | |
| VS-0525-XY1698 | Anti-Mouse CS Immunohistochemistry Kit | IHC | |
| VS-0525-XY1697 | Anti-Human CS Immunohistochemistry Kit | IHC | |
| VS-0525-XY1699 | Anti-Rat CS Immunohistochemistry Kit | IHC |
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