Recombinant Anti-ECSCR Vesicular Antibody, EV Displayed (VS-0425-YC187) (CAT#: VS-0425-YC187)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• ECSCR

• Host Animal
• Mouse

• Antibody Isotype
• IgG1

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein G

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Endothelial cell surface expressed chemotaxis and apoptosis regulator

• Biological Process
• Angiogenesis, Apoptosis, Chemotaxis, Differentiation

• Molecular Function
• Developmental protein

• Cellular Localization
• Vesicles, Plasma membrane, Nucleoplasm

• Introduction
• The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases.

• Alternative Names
• ARIA, ECSM2

• Gene ID
• 641700

• UniProt ID
• Q19T08

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