Recombinant Anti-EDNRB Vesicular Antibody, EV Displayed (VS-0425-YC362) (CAT#: VS-0425-YC362)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• EDNRB

• Host Animal
• Mouse

• Antibody Isotype
• IgG2b kappa

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Endothelin receptor type B

• Molecular Function
• G-protein coupled receptor, Receptor, Transducer

• Cellular Localization
• Plasma membrane, Cytosol

• Introduction
• The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.

• Alternative Names
• ETB, HSCR, HSCR2

• Gene ID
• 1910

• UniProt ID
• P24530

Select a product category from the dropdown menu below to view related products.