Recombinant Anti-ENTPD1 Vesicular Antibody, EV Displayed (VS-0425-YC617)
CAT#: VS-0425-YC617
The Recombinant Anti-ENTPD1 Vesicular Antibody, EV Displayed (VS-0425-YC617) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ENTPD1-expressed cells or tissues. ENTPD1 hydrolyzes extracellular ATP to AMP, with inhibition offering potential anticancer benefits.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to microtubules.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/14067/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human endometrium
Immunohistochemical staining of human endometrium shows strong cytoplasmic positivity with a granular pattern in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/79986/170655_B_5_3_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/14067/31810_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Fibroblasts
Staining: Medium
Intensity: Moderate
Mucosal lymphoid cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/14067/31810_A_9_3.jpg
Normal Tissue
Figure 5 Placenta
Cytotrophoblasts
Staining: High
Intensity: Strong
Quantity:>75%
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Hofbauer cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/14067/31810_A_1_7.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/14067/31810_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (HDLM-2, Karpas-707)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000138185-ENTPD1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ENTPD1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Ectonucleoside triphosphate diphosphohydrolase 1
- Molecular Function
- Hydrolase
- Cellular Localization
- Microtubules
- Introduction
- The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits.
- Alternative Names
- ATPDase, CD39, NTPDase-1, SPG64
- Gene ID
- 953
- UniProt ID
- P49961
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Datasheet
MSDS
COA
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Lot Number:
See other products for "ENTPD1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2248MZ | Recombinant Mouse Anti-Human ENTPD1 Antibody (clone 33B0) | IHC-P | Mouse antibody |
| HPAB-N0081-YC | Human Anti-ENTPD1 Recombinant Antibody (clone HH3/LH4) | Inhib | Humanized IgG |
| ZG-1073F | Rat Anti-ENTPD1 Antibody (clone R22) | FC | Rat IgG1 |
| VS3-FY501 | Recombinant Rabbit Anti-ENTPD1 Antibody (clone R09-3I2) | WB | Rabbit IgG |
| VS4-WK161 | Rabbit Anti-ENTPD1 Recombinant Antibody (clone 12D12) | ELISA, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1158 | Hi-Affi™ Rabbit Anti-ENTPD1 Recombinant Antibody (clone DS1158AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0177-CN-S(P) | Mouse Anti-ENTPD1 Recombinant Antibody; scFv Fragment (HPAB-0177-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0178-CN-S(P) | Mouse Anti-ENTPD1 Recombinant Antibody; scFv Fragment (HPAB-0178-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0179-CN-S(P) | Mouse Anti-ENTPD1 Recombinant Antibody; scFv Fragment (HPAB-0179-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0180-CN-S(P) | Human Anti-ENTPD1 Recombinant Antibody; scFv Fragment (HPAB-0180-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-M0475-YC-S(P) | Mouse Anti-ENTPD1 Recombinant Antibody (clone mAb1); scFv Fragment | Inhib | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0177-CN-F(E) | Mouse Anti-ENTPD1 Recombinant Antibody; Fab Fragment (HPAB-0177-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0178-CN-F(E) | Mouse Anti-ENTPD1 Recombinant Antibody; Fab Fragment (HPAB-0178-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-M0475-YC-F(E) | Mouse Anti-ENTPD1 Recombinant Antibody (clone mAb1); Fab Fragment | Inhib | Mouse Fab |
| HPAB-M0476-YC-F(E) | Mouse Anti-ENTPD1 Recombinant Antibody (clone mAb2); Fab Fragment | ELISA | Mouse Fab |
| HPAB-M0477-YC-F(E) | Mouse Anti-ENTPD1 Recombinant Antibody (clone mAb3); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY116 | Mouse Anti-ENTPD1 (clone mAb1) scFv-Fc Chimera | IA | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2295 | Anti-ENTPD1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2296 | Anti-Mouse ENTPD1 Immunohistochemistry Kit | IHC |
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