Recombinant Anti-EPHA10 Vesicular Antibody, EV Displayed (VS-0425-YC167)
CAT#: VS-0425-YC167
The Recombinant Anti-EPHA10 Vesicular Antibody, EV Displayed (VS-0425-YC167) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to EPHA10-expressed cells or tissues. The EPHA10 is a receptor tyrosine kinase, part of the ephrin receptor family involved in cell-cell communication regulation.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27497/59601_B_9_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27497/59601_A_8_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27497/59601_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27497/59601_A_6_6.jpg
Normal Tissue
Figure 5 Skin
Keratinocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Langerhans Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Melanocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27497/59601_B_8_1.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (BEWO, HDLM-2, SCLC-21H)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000183317-EPHA10
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- EPHA10
- Host Animal
- Mouse
- Antibody Isotype
- IgG2b kappa
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- EPH receptor A10
- Molecular Function
- Kinase, Receptor, Transferase, Tyrosine-protein kinase
- Introduction
- Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008]
- Alternative Names
- FLJ16103, FLJ33655
- Gene ID
- 284656
- UniProt ID
- Q5JZY3
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COA
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| TAB-378MZ-S(P) | Anti-Human EPHA10 Recombinant Antibody scFv Fragment (EPHA10_A1) | IHC, FC |
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| CAT | Product Name | Application | Type |
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