Recombinant Anti-EPHB3 Vesicular Antibody, EV Displayed (VS-0425-YC674)
CAT#: VS-0425-YC674
The Recombinant Anti-EPHB3 Vesicular Antibody, EV Displayed (VS-0425-YC674) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to EPHB3-expressed cells or tissues. EPHB3 is an ephrin receptor critical in nervous system development, binding ephrin-B ligands for bidirectional signaling.
Gene Expression
Normal Tissue
Figure 1 Skin 1
High expression in skin 1
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8184/22584_B_9_1_selected.jpg
Normal Tissue
Figure 2 Skin
Epidermal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34350/149854_B_5_8.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34350/149854_A_8_5.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (BEWO, HaCaT, OE19, SK-BR-3, T-47d)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182580-EPHB3
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- EPHB3
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- EPH receptor B3
- Biological Process
- Angiogenesis, Neurogenesis
- Molecular Function
- Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase
- Introduction
- Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010]
- Alternative Names
- ETK2, Hek2, Tyro6
- Gene ID
- 2049
- UniProt ID
- P54753
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Datasheet
MSDS
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1167 | Hi-Affi™ Rabbit Anti-EPHB3 Recombinant Antibody (clone DS1167AB) | WB, ICC, IP, FC | Rabbit IgG |
| MOR-1168 | Hi-Affi™ Rabbit Anti-Ephb3 Recombinant Antibody (clone DS1168AB) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0024CQ | Mouse Anti-EPHB3 Recombinant Antibody (HPAB-0024CQ) | WB, IP, FC | Mouse IgG, κ |
| MOB-254YJL | Rabbit Anti-EPHB3 Recombinant Antibody (clone CBE239) | FC | Rabbit IgG |
| ZG-0302J | Mouse Anti-EPHB3 Recombinant Antibody (ZG-0302J) | WB, IHC, ELISA | Mouse IgG |
| VS3-XY635 | Mouse Anti-EPHB3 Recombinant Antibody (clone 4A122D1) | ELISA, WB, IHC | Mouse IgG2a |
| VS7-HM879 | Mouse Anti-EPHB3 Recombinant Antibody (clone CBL242HM) | WB, IHC-p, IF, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0024CQ-S(P) | Mouse Anti-EPHB3 Recombinant Antibody; scFv Fragment (HPAB-0024CQ-S(P)) | WB, IP, FC | Mouse scFv |
| HPAB-0025CQ-S(P) | Mouse Anti-EPHB3 Recombinant Antibody; scFv Fragment (HPAB-0025CQ-S(P)) | WB, IP, FC | Mouse scFv |
| HPAB-0026CQ-S(P) | Mouse Anti-EPHB3 Recombinant Antibody; scFv Fragment (HPAB-0026CQ-S(P)) | WB, IP, FC | Mouse scFv |
| HPAB-0027CQ-S(P) | Mouse Anti-EPHB3 Recombinant Antibody; scFv Fragment (HPAB-0027CQ-S(P)) | WB, IP, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0024CQ-F(E) | Mouse Anti-EPHB3 Recombinant Antibody; Fab Fragment (HPAB-0024CQ-F(E)) | WB, IP, FC | Mouse Fab |
| HPAB-0025CQ-F(E) | Mouse Anti-EPHB3 Recombinant Antibody; Fab Fragment (HPAB-0025CQ-F(E)) | WB, IP, FC | Mouse Fab |
| HPAB-0026CQ-F(E) | Mouse Anti-EPHB3 Recombinant Antibody; Fab Fragment (HPAB-0026CQ-F(E)) | WB, IP, FC | Mouse Fab |
| HPAB-0027CQ-F(E) | Mouse Anti-EPHB3 Recombinant Antibody; Fab Fragment (HPAB-0027CQ-F(E)) | WB, IP, FC | Mouse Fab |
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|---|---|---|---|
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| VS-0724-YC1198 | AbPlus™ Anti-Ephb3 Magnetic Beads (VS-0724-YC1198) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC361 | CytoStream™ Rabbit Anti-EPHB3 Recombinant Antibody (VS13-YC361) | WB, ICC, IF, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2316 | Anti-EPHB3 Immunohistochemistry Kit | IHC |
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