Recombinant Anti-F2RL3 Vesicular Antibody, EV Displayed (VS-0425-YC434) (CAT#: VS-0425-YC434)
The Recombinant Anti-F2RL3 Vesicular Antibody, EV Displayed (VS-0425-YC434) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to F2RL3-expressed cells or tissues. The F2RL3 is a receptor involved in coagulation and inflammation, with hypomethylation linked to lung cancer.

(Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31401/1825_D4_82_cr5ac335fe2b88a_selected.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000127533-F2RL3
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- F2RL3
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- F2R like thrombin or trypsin receptor 3
- Biological Process
- Blood coagulation, Hemostasis
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Plasma membrane
- Introduction
- This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016]
- Alternative Names
- PAR4
- Gene ID
- 9002
- UniProt ID
- Q96RI0
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "F2RL3"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-3726z | Mouse Anti-F2RL3 Recombinant Antibody (clone 41H12) | WB, ELISA, IHC | Mouse IgG1 |
PABC-043 | Mouse Anti-F2RL3 Recombinant Antibody (clone P20.1) | ELISA | Mouse IgG |
MOB-1712CT | Recombinant Mouse anti-Human F2RL3 Monoclonal antibody (EML799) | ICC/IF, WB |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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