Recombinant Anti-F2RL3 Vesicular Antibody, EV Displayed (VS-0425-YC434)
CAT#: VS-0425-YC434
The Recombinant Anti-F2RL3 Vesicular Antibody, EV Displayed (VS-0425-YC434) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to F2RL3-expressed cells or tissues. The F2RL3 is a receptor involved in coagulation and inflammation, with hypomethylation linked to lung cancer.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31401/1825_D4_82_cr5ac335fe2b88a_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (HEL, HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000127533-F2RL3
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- F2RL3
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- F2R like thrombin or trypsin receptor 3
- Biological Process
- Blood coagulation, Hemostasis
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Plasma membrane
- Introduction
- This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016]
- Alternative Names
- PAR4
- Gene ID
- 9002
- UniProt ID
- Q96RI0
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "F2RL3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3726z | Mouse Anti-F2RL3 Recombinant Antibody (clone 41H12) | WB, ELISA, IHC | Mouse IgG1 |
| PABC-043 | Mouse Anti-F2RL3 Recombinant Antibody (clone P20.1) | ELISA | Mouse IgG |
| MOB-1712CT | Recombinant Mouse anti-Human F2RL3 Monoclonal antibody (EML799) | ICC, IF, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-043 | Mouse Anti-F2RL3 Recombinant Antibody (clone P20.1); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-043 | Mouse Anti-F2RL3 Recombinant Antibody (clone P20.1); scFv Fragment | ELISA | Mouse scFv |
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