Recombinant Anti-FCGR1A Vesicular Antibody, EV Displayed (VS-0425-YC345)
CAT#: VS-0425-YC345
The Recombinant Anti-FCGR1A Vesicular Antibody, EV Displayed (VS-0425-YC345) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to FCGR1A-expressed cells or tissues. The FCGR1A is a high-affinity Fc receptor critical for immune responses.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line THP-1
Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26910/2005_G4_1_selected.jpg
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- FCGR1A
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Fc gamma receptor Ia
- Biological Process
- Immunity, Innate immunity
- Molecular Function
- IgG-binding protein, Receptor
- Cellular Localization
- Vesicles, Golgi apparatus, Plasma membrane
- Introduction
- This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
- Alternative Names
- CD64, CD64A, FCG1, FcgammaRI, FcgammaRIa, FCGR1
- Gene ID
- 2209
- UniProt ID
- P12314
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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