Recombinant Anti-FPR1 Vesicular Antibody, EV Displayed (VS-0425-YC412)
CAT#: VS-0425-YC412
The Recombinant Anti-FPR1 Vesicular Antibody, EV Displayed (VS-0425-YC412) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to FPR1-expressed cells or tissues. The FPR1 is a GPCR in mammalian phagocytes, mediating response to microbial invasion and defense processes.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61744/1413_D6_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells and strong cytoplasmic positivity in peripheral leukocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/ihc_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_A_9_3.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_A_4_6.jpg
Normal Tissue
Figure 5 Bone marrow
Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_B_5_4.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (LHCN-M2, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171051-FPR1
❮
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- FPR1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Formyl peptide receptor 1
- Biological Process
- Chemotaxis
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Golgi apparatus, Nucleoplasm, Nucleoli
- Introduction
- This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]
- Alternative Names
- FMLP, FPR
- Gene ID
- 2357
- UniProt ID
- P21462
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "FPR1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1631z | Mouse Anti-FPR1 Recombinant Antibody (clone 33D10) | WB, IF | Mouse IgG1 |
| PABL-097 | Human Anti-FPR1 Recombinant Antibody (PABL-097) | FC, FuncS | Human IgG |
| MRO-1872-CN | Rabbit Anti-FPR1 Polyclonal Antibody (MRO-1872-CN) | WB, IF, IHC | Rabbit IgG |
| MRO-1873-CN | Rabbit Anti-FPR1 Polyclonal Antibody (MRO-1873-CN) | WB, IF, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-097 | Human Anti-FPR1 Recombinant Antibody scFv Fragment (PSBL-097) | FC, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-097 | Human Anti-FPR1 Recombinant Antibody Fab Fragment (PFBL-097) | FC, FuncS | Human Fab |
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