Human Anti-FPR1 Recombinant Antibody (PABL-097)
CAT#: PABL-097
Recombinant Human Antibody is capable of binding to FPR1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-FPR1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-FPR1 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61744/1413_D6_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells and strong cytoplasmic positivity in peripheral leukocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/ihc_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_A_9_3.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_A_4_6.jpg
Normal Tissue
Figure 5 Bone marrow
Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_B_5_4.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (LHCN-M2, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171051-FPR1
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Specifications
- Immunogen
- Human formyl peptide receptor 1
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human FPR1
- Species Reactivity
- Human
- Applications
- FC, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody was validated for Flow Cytometry and Inhibition. For details, refer to published data.
Target
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Stable and robust
Because of its robustness, this antibody is a useful tool for a range of tasks. It is reliable at all times.
Response across species
Tested on multiple cell lines, this antibody's high specificity and reactivity were retained. Very flexible.
Exceptionally acute detection
Our higher signal-to-noise ratio demonstrated the antibody's sensitivity, especially under difficult detection conditions.
Q&As
-
What are the "housekeeping" antibodies?
A: Housekeeping antibodies target proteins consistently expressed at stable levels and are used as loading controls in applications like Western blots.
-
How does antibody valency influence binding?
A: Antibody bivalency increases binding avidity and stability when interacting with multivalent antigens.
-
Could antibodies be used to detect protein-protein interactions?
A: Co-immunoprecipitation with specific antibodies can help study protein-protein interactions effectively.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "FPR1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1631z | Mouse Anti-FPR1 Recombinant Antibody (clone 33D10) | WB, IF | Mouse IgG1 |
| MRO-1872-CN | Rabbit Anti-FPR1 Polyclonal Antibody (MRO-1872-CN) | WB, IF, IHC | Rabbit IgG |
| MRO-1873-CN | Rabbit Anti-FPR1 Polyclonal Antibody (MRO-1873-CN) | WB, IF, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-097 | Human Anti-FPR1 Recombinant Antibody scFv Fragment (PSBL-097) | FC, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-097 | Human Anti-FPR1 Recombinant Antibody Fab Fragment (PFBL-097) | FC, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC412 | Recombinant Anti-FPR1 Vesicular Antibody, EV Displayed (VS-0425-YC412) | ELISA, FC, Cell-uptake |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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