Human Anti-FPR1 Recombinant Antibody (PABL-097) (CAT#: PABL-097)
Recombinant Human Antibody is capable of binding to FPR1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-FPR1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-FPR1 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RH-30
(Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/61744/1413_D6_1_selected.jpg
(Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/61744/1413_D6_1_selected.jpg
Figure 2 IHC staining of human colon
(Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells and strong cytoplasmic positivity in peripheral leukocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/ihc_selected.jpg
(Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells and strong cytoplasmic positivity in peripheral leukocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/ihc_selected.jpg
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_A_9_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_A_9_3.jpg
Figure 4 Testis
(Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_A_4_6.jpg
(Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_A_4_6.jpg
Figure 5 Bone marrow
(Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_B_5_4.jpg
(Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_B_5_4.jpg
Figure 6 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_A_7_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46550/105710_A_7_8.jpg
Figure 7 RNA cell line category: Group enriched (LHCN-M2, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171051-FPR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171051-FPR1
Specifications
- Immunogen
- Human formyl peptide receptor 1
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human FPR1
- Species Reactivity
- Human
- Applications
- FC, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody was validated for Flow Cytometry and Inhibition. For details, refer to published data.
Target
- Alternative Names
- FPR1; formyl peptide receptor 1; FPR; FMLP; fMet-Leu-Phe receptor; fMLP receptor; N-formylpeptide chemoattractant receptor
- Gene ID
- 2357
- UniProt ID
- P21462
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "FPR1"
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Please select product type
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1631z | Mouse Anti-FPR1 Recombinant Antibody (clone 33D10) | WB, IF | Mouse IgG1 |
| MRO-1872-CN | Rabbit Anti-FPR1 Polyclonal Antibody (MRO-1872-CN) | WB, IF, IHC | Rabbit IgG |
| MRO-1873-CN | Rabbit Anti-FPR1 Polyclonal Antibody (MRO-1873-CN) | WB, IF, IHC, FC | Rabbit IgG |
Customer Reviews and Q&As
Customer Review
Q&As
Stable and robust
Because of its robustness, this antibody is a useful tool for a range of tasks. It is reliable at all times.
Response across species
Tested on multiple cell lines, this antibody's high specificity and reactivity were retained. Very flexible.
Exceptionally acute detection
Our higher signal-to-noise ratio demonstrated the antibody's sensitivity, especially under difficult detection conditions.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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