Recombinant Anti-GABRG2 Vesicular Antibody, EV Displayed (VS-0425-YC704) (CAT#: VS-0425-YC704)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• GABRG2

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Rat

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Gamma-aminobutyric acid type A receptor subunit gamma2

• Biological Process
• Ion transport, Transport

• Molecular Function
• Chloride channel, Ion channel

• Introduction
• Enables GABA-A receptor activity and chloride channel activity. Contributes to GABA receptor activity. Involved in several processes, including GABAergic synaptic transmission; cellular response to zinc ion; and response to anesthetic. Located in cell surface; dendrite membrane; and inhibitory synapse. Part of GABA receptor complex. Is active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic specialization membrane. Biomarker of fetal alcohol spectrum disorder and hepatic encephalopathy. Human ortholog(s) of this gene implicated in alcohol dependence; alcoholic liver cirrhosis; amphetamine abuse; brain disease (multiple); and heroin dependence. Orthologous to human GABRG2 (gamma-aminobutyric acid type A receptor subunit gamma2).

• Gene ID
• 29709

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