Recombinant Anti-GLRA1 Vesicular Antibody, EV Displayed (VS-0425-YC64) (CAT#: VS-0425-YC64)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• GLRA1

• Host Animal
• Rabbit

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Rat, Mouse, Pig, Zebrafish

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Glycine receptor alpha 1

• Biological Process
• Ion transport, Transport

• Molecular Function
• Chloride channel, Ion channel, Ligand-gated ion channel, Receptor

• Cellular Localization
• Vesicles, Plasma membrane

• Introduction
• The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Multiple transcript variants encoding different isoforms have been found.

• Alternative Names
• STHE

• Gene ID
• 2741

• UniProt ID
• P23415

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