Recombinant Anti-GLRA1 Vesicular Antibody, EV Displayed (VS-0425-YC64)
CAT#: VS-0425-YC64
The Recombinant Anti-GLRA1 Vesicular Antibody, EV Displayed (VS-0425-YC64) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to GLRA1-expressed cells or tissues. The GLRA1 is a glycine receptor subunit involved in inhibitory synapse functions, with mutations leading to startle disease.
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- GLRA1
- Host Animal
- Rabbit
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Rat, Mouse, Pig, Zebrafish
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Glycine receptor alpha 1
- Biological Process
- Ion transport, Transport
- Molecular Function
- Chloride channel, Ion channel, Ligand-gated ion channel, Receptor
- Cellular Localization
- Vesicles, Plasma membrane
- Introduction
- The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Multiple transcript variants encoding different isoforms have been found.
- Alternative Names
- STHE
- Gene ID
- 2741
- UniProt ID
- P23415
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COA
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See other products for "GLRA1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0584MZ | Recombinant Mouse Anti-Human GLRA1 Antibody | WB | Mouse antibody |
| VS-0223-WK34 | Rabbit Anti-GLRA1 Recombinant Antibody (VS-0223-WK34) | WB, ICC, IHC, IHC-P | Rabbit IgG |
| VS-0223-WK35 | Guinea pig Anti-GLRA1 Recombinant Antibody (VS-0223-WK35) | WB, IHC | Guinea pig IgG |
| VS-0223-WK36 | Rabbit Anti-GLRA1 Recombinant Antibody (VS-0223-WK36) | ICC, IHC | Rabbit IgG |
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