Recombinant Anti-GP1BA Vesicular Antibody, EV Displayed (VS-0425-YC574)
CAT#: VS-0425-YC574
The Recombinant Anti-GP1BA Vesicular Antibody, EV Displayed (VS-0425-YC574) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to GP1BA-expressed cells or tissues. GP1BA is the alpha subunit of glycoprotein Ib, a receptor for von Willebrand factor (VWF) involved in platelet adhesion to vascular injury sites. Mutations in this gene cause Bernard-Soulier syndromes and platelet-type von Willebrand disease.
Gene Expression
Normal Tissue
Figure 1 Bone marrow
Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2496/6301_B_6_4.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (HEL)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185245-GP1BA
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- GP1BA
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Glycoprotein Ib platelet subunit alpha
- Biological Process
- Blood coagulation, Cell adhesion, Hemostasis
- Introduction
- Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease.
- Alternative Names
- CD42b, GP1B, GPIbalpha
- Gene ID
- 2811
- UniProt ID
- P07359
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC574. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "GP1BA"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-413-F(E) | Recombinant Anti-human GP1BA Antibody Fab Fragment | ELISA, IF, FuncS | Fab |
| MHH-413-F(E) | Recombinant Human Anti-human GP1BA Antibody Fab Fragment | IF, Neut, FuncS | Fab |
| HPAB-0367-YJ-F(E) | Mouse Anti-GP1BA Recombinant Antibody; Fab Fragment (HPAB-0367-YJ-F(E)) | ELISA, FC, WB, Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-413-S(P) | Recombinant Anti-human GP1BA Antibody scFv Fragment | FC, Neut, Funcs | scFv |
| MHH-413-S(P) | Recombinant Human Anti-human GP1BA Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| HPAB-0367-YJ-S(P) | Mouse Anti-GP1BA Recombinant Antibody; scFv Fragment (HPAB-0367-YJ-S(P)) | ELISA, FC, WB, Inhib | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-413 | Recombinant Human Anti-human GP1BA Antibody | ELISA, FacS, FuncS | IgG |
| FN-141CQ | Human Anti-GP1BA Recombinant Antibody (clone CBL-1310) | FuncS, Block | Human IgG1 |
| FAMAB-0555WJ | Human Anti-GP1BA Recombinant Antibody (clone DM1) | ELISA, WB | Human IgG |
| ZG-506C | Mouse Anti-GP1BA Recombinant Antibody (clone 6.52.7.6) | ELISA | Mouse IgG1, κ |
| VS2-QX5 | Mouse Anti-GP1BA Recombinant Antibody (clone PAB-5) | IF | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-883CQ | Mouse Anti-GP1BA Recombinant Antibody (clone HIP1) | FC, FuncS, Neut, IHC, WB | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1482 | Hi-Affi™ Rabbit Anti-GP1BA Recombinant Antibody (clone DS1482AB) | WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC458 | CytoStream™ Mouse Anti-GP1BA Recombinant Antibody (VS13-YC458) | IHC-P, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2873 | Anti-GP1BA Immunohistochemistry Kit | IHC | |
| VS-0525-XY2874 | Anti-Mouse GP1BA Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: WB, IF, FuncS
-3-1.png)
Application: SPR, Inhib, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FC, Inhib, FuncS
Application: ELISA, IHC, IF, IP
Application: ELISA, FuncS
Application: ELISA, WB, IF, FC, IP
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
