Recombinant Anti-GPR87 Vesicular Antibody, EV Displayed (VS-0425-YC499) (CAT#: VS-0425-YC499)
The Recombinant Anti-GPR87 Vesicular Antibody, EV Displayed (VS-0425-YC499) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to GPR87-expressed cells or tissues. GPR87 is a G protein-coupled receptor overexpressed in lung cancer and regulated by p53. This protein indicates potential oncogenic roles.
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Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, mitochondria & lipid droplets.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66313/1247_C12_1_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, mitochondria & lipid droplets.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66313/1247_C12_1_selected.jpg
Figure 2 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm, mitochondria & lipid droplets.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66313/1320_D4_1_red_green.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm, mitochondria & lipid droplets.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66313/1320_D4_1_red_green.jpg
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, mitochondria & lipid droplets.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66313/1244_C12_3_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, mitochondria & lipid droplets.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66313/1244_C12_3_red_green.jpg
Figure 4 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RT4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138271-GPR87
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138271-GPR87
Recombinant Antibody
- Application
- Cyt, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- GPR87
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- G protein-coupled receptor 87
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Lipid droplets, Mitochondria, Nucleoplasm
- Introduction
- This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589). [provided by RefSeq, Nov 2011]
- Alternative Names
- GPR95
- Gene ID
- 53836
- UniProt ID
- Q9BY21
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Mouse Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-002CT | Mouse Anti-GPR87 Recombinant Antibody (TAB-002CT) | WB | Mouse IgG1 |
| TAB-002CT-S(P) | Mouse Anti-GPR87 Recombinant Antibody; scFv Fragment (TAB-002CT-S(P)) | WB | Mouse scFv |
| TAB-002CT-F(E) | Mouse Anti-GPR87 Recombinant Antibody; Fab Fragment (TAB-002CT-F(E)) | WB | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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