Recombinant Anti-GYPB Vesicular Antibody, EV Displayed (VS-0425-YC745)
CAT#: VS-0425-YC745
The Recombinant Anti-GYPB Vesicular Antibody, EV Displayed (VS-0425-YC745) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to GYPB-expressed cells or tissues. GYPB is an erythrocyte membrane sialoglycoprotein bearing blood group antigens, with multiple variants from gene recombinations with GYPA.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enriched (HEL)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000250361-GYPB
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- GYPB
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Glycophorin B (MNS blood group)
- Molecular Function
- Blood group antigen
- Introduction
- Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.
- Alternative Names
- CD235b, GPB, MNS, SS
- Gene ID
- 2994
- UniProt ID
- P06028
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1363z | Mouse Anti-GYPB Recombinant Antibody (clone 10B6) | WB, IP, IF, FC | Mouse IgM |
| FAMAB-0165CQ | Mouse Anti-GYPB Recombinant Antibody (clone N92) | ELISA, WB | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0165CQ-F(E) | Mouse Anti-GYPB Recombinant Antibody (clone N92); Fab Fragment | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
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| FAMAB-0165CQ-S(P) | Mouse Anti-GYPB Recombinant Antibody (clone N92); scFv Fragment | ELISA, WB | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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