Recombinant Anti-ITGA3 Vesicular Antibody, EV Displayed (VS-0425-YC678) (CAT#: VS-0425-YC678)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• ITGA3

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Monkey

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Integrin subunit alpha 3

• Biological Process
• Cell adhesion

• Molecular Function
• Integrin, Receptor

• Cellular Localization
• Plasma membrane

• Introduction
• The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]

• Alternative Names
• CD49c, GAP-B3, MSK18, VCA-2, VLA3a

• Gene ID
• 3675

• UniProt ID
• P26006

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