Recombinant Anti-KCNH2 Vesicular Antibody, EV Displayed (VS-0425-YC559) (CAT#: VS-0425-YC559)

The Recombinant Anti-KCNH2 Vesicular Antibody, EV Displayed (VS-0425-YC559) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to KCNH2-expressed cells or tissues. KCNH2 is a voltage-activated potassium channel related to arrhythmias like long QT syndrome.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
RNA Expression

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • KCNH2
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Potassium voltage-gated channel subfamily H member 2
  • Biological Process
  • Ion transport, Potassium transport, Transport
  • Molecular Function
  • Ion channel, Potassium channel, Voltage-gated channel
  • Introduction
  • This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified.
  • Alternative Names
  • erg1, HERG, Kv11.1, LQT2

Downloads

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CAT Product Name Application Type
HPAB-0475-FY Mouse Anti-KCNH2 Recombinant Antibody (HPAB-0475-FY) IF, ELISA Mouse IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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