Recombinant Anti-LILRB2 Vesicular Antibody, EV Displayed (VS-0425-YC15)
CAT#: VS-0425-YC15
The Recombinant Anti-LILRB2 Vesicular Antibody, EV Displayed (VS-0425-YC15) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LILRB2-expressed cells or tissues. The LILRB2 belongs to the leukocyte immunoglobulin-like receptor family. It is a protein expressed on immune cells, which binds MHC class I molecules to transmit inhibitory signals, regulating immune responses and limiting autoreactivity.
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LILRB2
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Leukocyte immunoglobulin like receptor B2
- Biological Process
- Adaptive immunity, Immunity
- Molecular Function
- Receptor
- Introduction
- This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
- Alternative Names
- CD85d, ILT4, LIR-2, LIR2, MIR-10, MIR10
- Gene ID
- 10288
- UniProt ID
- Q8N423
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See other products for "LILRB2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1097CT | Recombinant Mouse anti-Human LILRB2 Monoclonal antibody (EML1069) | WB | |
| FN-169CQ | Recombinant Rat Anti-LILRB2 Antibody (42D1) | FC, FuncS, IF | Rat IgG2a, κ |
| VS-0723-WK22 | Human Anti-LILRB2 Recombinant Antibody (VS-0723-WK22) | ELISA, FC | Human IgG4 |
| VS-0723-WK76 | Human Anti-LILRB2 Recombinant Antibody (VS-0723-WK76) | FC | Chimeric (rabbit/human) IgG1 |
| VS7-0425-WR297 | Mouse Anti-LILRB2 Recombinant Antibody (clone 2G7E11) | WB, FC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1697CQ | Recombinant Mouse Anti-LILRB2 Antibody (CBL608) | WB, FC, CyTOF, Neut | IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FN-161CQ | Recombinant Rat Anti-LILRB2 Antibody (CBL-1322) | FC, FuncS, Neut | Rat IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY159 | CytoStream™ Mouse Anti-LILRB2 Recombinant Antibody (clone 287219) | FC | Mouse IgG2a, kappa |
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