


Anti-LILRB2 Recombinant Antibody Products

Anti-LILRB2 Products
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- Species Reactivity: Human
- Application: WB
- Human Anti-LILRB2 Recombinant Antibody (VS-0723-WK76) (VS-0723-WK76)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG1
- Application: FC
- Human Anti-LILRB2 Recombinant Antibody (VS-0723-WK22) (VS-0723-WK22)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG4
- Application: ELISA, FC
- Recombinant Rat Anti-LILRB2 Antibody (42D1) (FN-169CQ)
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- Species Reactivity: Human, Non-human primate
- Type: Rat IgG2a, κ
- Application: FC, FuncS, IF
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- Species Reactivity: Human
- Type: Rat IgM
- Application: FC, FuncS, Neut
- Recombinant Mouse Anti-LILRB2 Antibody (CBL608) (NEUT-1697CQ)
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- Species Reactivity: Human
- Type: IgG2a
- Application: WB, FC, CyTOF, Neut
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- Species Reactivity: Human
- Target: LILRB2
- Host Animal: Human
- Application: ELISA, FC, Cell-uptake
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- Species Reactivity: Human
- Type: Mouse IgG2a, kappa
- Application: FC
- Mouse Anti-LILRB2 Recombinant Antibody (clone 2G7E11) (VS7-0425-WR297)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, FC
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For Research Use Only. Not For Clinical Use.
Designed for optimal precision and dependability, Creative Biolabs provides a large spectrum of highly performing recombinant antibodies targeting LILRB2. These antibodies allow strong and repeatable results by using contemporary engineering techniques to offer better stability and specificity. This makes them vital instruments for researchers and developers striving to progress focused cancer treatments since they enable the identification and creation of creative therapeutic approaches.
LILRB2: An Attractive Target for Cancer Therapy
Found on myeloid cells, LILRB2 mediates immunosuppression in cancer, causes neurodegeneration by interacting with β-amyloid and myelin inhibitors in Alzheimer's, and helps to dysregulate immune responses in autoimmune diseases including SLE and RA. Its capacity to kill immune cells qualifies it as a potential therapeutic target in several types of diseases.
Alternative Names
Leukocyte immunoglobulin-like receptor subfamily B member 2; ILT4, MIR10, LIR2, MIR-10, LIR-2, leukocyte immunoglobulin like receptor B2, ILT-4, CD85D.
Background
LILRB2 encodes an immune receptor that plays a role in immune regulation, particularly in inhibiting immune cell activation. This receptor is involved in controlling the activation of monocytes and dendritic cells, helping to prevent excessive immune responses and autoimmunity. LILRB2 is part of a broader family of immunoglobulin-like receptors that regulate immune tolerance and inflammation. It plays a significant role in maintaining a balance between immunity and tolerance in various diseases, including cancer and autoimmune disorders.
CD markers
Membrane
Cell type enhanced (Kupffer cells, Macrophages, monocytes, Langerhans cells)
Group enriched (non-classical monocyte, intermediate monocyte, neutrophil, classical monocyte)
Not detected
Binds PTPN6 when phosphorylated. Binds FCGR1A. Interacts with peptide-bound HLA-G-B2M; this interaction is direct (PubMed:16455647). Interacts with peptide-bound HLA-F-B2M; this interaction is direct (PubMed:11169396).
Receptor
Anti-LILRB2 rAb Products
Creative Biolabs provides a rigorously designed array of recombinant anti-LILRB2 antibodies developed for excellent specificity and affinity, meeting a wide range of research demands. Our antibodies are produced based on a robust platform and have become cutting-edge tools that speed up scientific discovery and make it easier to develop novel therapies.
Table 1. Featured anti-LILRB2 recombinant antibody products at Creative Biolabs.
Cat. No. | Product Name | Target Species | Host Species | Applications |
NEUT-1697CQ | Recombinant Mouse Anti-LILRB2 Antibody (CBL608) | Human | Mouse IgG2a | WB, FC, Neut, etc. |
VS-0723-WK76 | Human Anti-LILRB2 Recombinant Antibody (VS-0723-WK76) | Human | Human Chimeric (rabbit/human) IgG1 | FC |
VS-0723-WK22 | Human Anti-LILRB2 Recombinant Antibody (VS-0723-WK22) | Human | Human IgG4 | ELISA, FC |
VS-0225-XY159 | CytoStream™ Mouse Anti-LILRB2 Recombinant Antibody (clone 287219) | Human | Mouse IgG2a, kappa | FC |
MOB-1097CT | Recombinant Mouse anti-Human LILRB2 Monoclonal antibody (EML1069) | Human | Mouse | WB |
Creative Quality Control
To guarantee the dependability of its anti-LILRB2 recombinant antibodies, Creative Biolabs applies rigorous quality control all throughout the manufacturing process. Rigorous testing and validation methods confirm the remarkable selectivity, high binding affinity, and optimal performance of our antibodies over a broad spectrum of research uses, therefore guaranteeing consistent and accurate results.
Fig.1 SDS-PAGE analysis of anti-LILRB2 antibody
(Cat# NEUT-1697CQ, Creative Biolabs).
Customer Reviews

Recombinant Mouse Anti-LILRB2 Antibody (CBL608) (NEUT-1697CQ)

Human Anti-LILRB2 Recombinant Antibody (VS-0723-WK22) (VS-0723-WK22)
rAb Production
Creative Biolabs provides consistent antibody production for worldwide clients by using creative and effective recombinant antibody producing technologies.
Featured Anti-LILRB2 Recombinant Antibody Production Platforms
Fig.2 Milligram-scale anti-LILRB2 recombinant antibody production.
Fig.3 Gram-scale anti-LILRB2 recombinant antibody production.
rAb Modalities
Creative Biolabs offers a large range of premium anti-LILRB2 recombinant antibodies, carefully engineered in several forms to satisfy the needs of scientists all over.
Fig.4 Full-length anti-LILRB2 recombinant antibody production and modalities.
LILRB2-Targeted Drug Information
Table 2. Public drug targeting LILRB2.
Company | Research phase | Classification | Condition |
Agenus (Originator) Merck & Co Merck & Co. (Merck & Co) |
Phase II |
Cancer Immunotherapy Human Monoclonal Antibodies |
Cancer, colorectal (adenocarcinoma) Cancer, kidney (renal cell carcinoma) Cancer, lung (non-small cell) (NSCLC) Cancer, lung (small cell) (SCLC) (extensive) Cancer, ovary Cancer, solid tumor Esophageal carcinoma (squamous cell) Melanoma |
OncoResponse (Originator) | Phase I/II |
Cancer Immunotherapy Humanized Monoclonal Antibodies |
Cancer, solid tumor |
NGM Biopharmaceuticals (Originator) | Phase I/II |
Bispecific Antibodies Cancer Immunotherapy Humanized Monoclonal Antibodies |
Cancer, colorectal Cancer, solid tumor |
Celgene Jounce Therapeutics (Originator) |
Phase I/II |
Cancer Immunotherapy Humanized Monoclonal Antibodies |
Cancer Cancer, biliary Cancer, head and neck (squamous cell carcinoma) Cancer, kidney (renal cell carcinoma, clear cell) Cancer, lung (non-small cell) (NSCLC) Cancer, ovary Cancer, skin Cancer, solid tumor Sarcoma Triple negative breast cancer |
SparX Biopharmaceutical (Originator) | Phase I |
Bispecific Antibodies Cancer Immunotherapy |
Cancer, colorectal Cancer, head and neck (squamous cell carcinoma) Cancer, kidney (renal cell carcinoma) Cancer, solid tumor |
Elpiscience BioPharma (Originator) | Phase I |
Cancer Immunotherapy Monoclonal Antibodies |
Cancer, solid tumor |
Bristol-Myers Squibb (Originator) | Phase I |
Cancer Immunotherapy Monoclonal Antibodies |
Cancer, solid tumor |
Biosion (Originator) Celldex Therapeutics (Originator) |
Phase I |
Bispecific Antibody Fusions Cancer Immunotherapy Humanized Monoclonal Antibodies Single-Chain V-Domain Antibody Fragment (scFv) |
Cancer, solid tumor |
ImmunOs Therapeutics (Originator) | Phase I |
Biotechnology Medicines Cancer Immunotherapy |
Cancer, solid tumor Hematologic-blood cancer |
(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)
Please reach out to us at your convenience for further details or to request information regarding our anti-LILRB2 recombinant antibody offerings.