Recombinant Anti-LILRB3 Vesicular Antibody, EV Displayed (VS-0425-YC93)
CAT#: VS-0425-YC93
The Recombinant Anti-LILRB3 Vesicular Antibody, EV Displayed (VS-0425-YC93) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LILRB3-expressed cells or tissues. The LILRB3 is a member of the leukocyte immunoglobulin-like receptor family, regulating immune response through inhibitory signaling.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26985/2030_C6_3_selected.jpg
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Recombinant Antibody
- Application
- Cyt, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LILRB3
- Host Animal
- Mouse
- Antibody Isotype
- IgG1 kappa
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein G
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Leukocyte immunoglobulin like receptor B3
- Biological Process
- Adaptive immunity, Immunity
- Molecular Function
- Receptor
- Cellular Localization
- Plasma membrane, Cytosol
- Introduction
- This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
- Alternative Names
- HL9; ILT5; LIR3; PIRB; CD85A; ILT-5; LIR-3; PIR-B; LILRA6
- Gene ID
- 11025
- UniProt ID
- O75022
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2777z | Mouse Anti-LILRB3 Recombinant Antibody (clone 30F12) | WB, FC | Mouse IgG2 |
| MOB-1098CT | Recombinant Mouse anti-Human LILRB3 Monoclonal antibody (5G0) | FC | |
| HPAB-N0362-YC | Mouse Anti-LILRB3 Recombinant Antibody (HPAB-N0362-YC) | ELISA, FuncS | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-492CL | Human Anti-LILRB3 Recombinant Antibody (TAB-492CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-708LC | Mouse Anti-LILRB3 Recombinant Antibody (TAB-708LC) | Cyt, FC, FuncS | Mouse IgG1, κ |
| TAB-708LC-S(P) | Mouse Anti-LILRB3 Recombinant Antibody; scFv Fragment (TAB-708LC-S(P)) | ELISA, FC | Mouse scFv |
| TAB-708LC-F(E) | Mouse Anti-LILRB3 Recombinant Antibody; Fab Fragment (TAB-708LC-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4307 | Hi-Affi™ Recombinant Rabbit Anti-LILRB3 Monoclonal Antibody (SI396DS) | ELISA | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0362-YC-S(P) | Mouse Anti-LILRB3 Recombinant Antibody; scFv Fragment (HPAB-N0362-YC-S(P)) | ELISA, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0362-YC-F(E) | Mouse Anti-LILRB3 Recombinant Antibody; Fab Fragment (HPAB-N0362-YC-F(E)) | ELISA, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4031 | Anti-LILRB3 Immunohistochemistry Kit | IHC |
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