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LILRB3
Loading...Anti-LILRB3 Products
- Mouse Anti-LILRB3 Recombinant Antibody (HPAB-N0362-YC) (HPAB-N0362-YC)
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- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: ELISA, FuncS
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- Mouse Anti-LILRB3 Recombinant Antibody; scFv Fragment (HPAB-N0362-YC-S(P)) (HPAB-N0362-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FuncS
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- Mouse Anti-LILRB3 Recombinant Antibody; Fab Fragment (HPAB-N0362-YC-F(E)) (HPAB-N0362-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FuncS
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- Anti-LILRB3 Immunohistochemistry Kit (VS-0525-XY4031)
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- Species Reactivity: Human
- Target: LILRB3
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
The LILRB3 gene encodes a protein that is part of the leukocyte immunoglobulin-like receptor (LILR) family. These receptors are found on immune cells and play a role in regulating immune responses. Specifically, LILRB3 is involved in modulating immune cell activity, and has been investigated in relation to it's impact on certain immune responses. Further research shows it to modulate Fc Receptor mediated functions of neutrophils. It is located in the 19q13.4 chromosomal region, which is a cluster of genes associated with immune function. The protein it produces is a transmembrane receptor that can interact with major histocompatibility complex (MHC) class I molecules. This interaction can have inhibitory effects on immune cell activation.
Protein class
CD markers
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Group enriched (Macrophages, Kupffer cells, monocytes, Hofbauer cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Not detected
Interaction
Interacts with LYN, PTPN6/SHP-1 and PTPN11/SHP-2.
Molecular function
Receptor
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