Recombinant Anti-LTBR Vesicular Antibody, EV Displayed (VS-0425-YC405)
CAT#: VS-0425-YC405
The Recombinant Anti-LTBR Vesicular Antibody, EV Displayed (VS-0425-YC405) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LTBR-expressed cells or tissues. The LTBR is a receptor in the TNF receptor superfamily, involved in immune responses and linked to carcinogenesis.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line
Immunofluorescent staining of human cell line RT4 shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61617/1766_D5_3_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26202/if_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human spleen
Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells of the red pulp.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26202/ihc_selected.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26202/58102_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26202/58102_A_4_6.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26202/58102_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HHSteC)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000111321-LTBR
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LTBR
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Lymphotoxin beta receptor
- Biological Process
- Apoptosis, Host-virus interaction
- Molecular Function
- Receptor
- Cellular Localization
- Golgi apparatus
- Introduction
- This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis.
- Alternative Names
- D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3
- Gene ID
- 4055
- UniProt ID
- P36941
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Datasheet
MSDS
COA
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See other products for "LTBR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2179z | Mouse Anti-LTBR Recombinant Antibody (clone 28H4) | WB, FC | Mouse IgG1 |
| PABL-636 | Human Anti-LTBR Recombinant Antibody (clone BHA10) | WB, IF, FuncS | Human IgG |
| MOB-1634MZ | Recombinant Mouse Anti-Human LTBR Antibody (clone NN0572-4U35) | FC, WB | Mouse antibody |
| FN-022CQ | Recombinant Rat Anti-LTBR Antibody (3C8) | FC, FuncS, WB | Rat IgG1, κ |
| VS7-0425-WR321 | Mouse Anti-LTBR Recombinant Antibody (clone 1D1C5C8) | WB, FC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-504CL | Human Anti-LTBR Recombinant Antibody (TAB-504CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-631 | Human Anti-LTBR Recombinant Antibody (clone BHA10); Fab Fragment | WB, IF, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-631 | Human Anti-LTBR Recombinant Antibody (clone BHA10); scFv Fragment | WB, IF, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0331MZ | Chicken Anti-LTBR Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-098LC | Recombinant Rat Anti-Mouse Ltbr Agonist Antibody (5G11) | IP | Rat antibody |
| MOB-099LC | Recombinant Mouse Anti-Human LTBR Agonist Antibody (CBE11) | ELISA, FunS, WB, IP | Mouse antibody |
| MOB-100LC | Recombinant Humanized Anti-Human LTBR Agonist Antibody (huCBE11) | ELISA, FunS, WB, IP | Humanized antibody |
| VS-0724-XY34 | Rat Anti-Ltbr Agonistic Antibody (clone 4H8 WH2) | FC, Functional assays | Rat IgG2a |
| VS-0724-XY35 | Mouse Anti-LTBR Agonistic Antibody (VS-0724-XY35) | Agonistic assays | Mouse IgG1 |
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