Recombinant Anti-MSR1 Vesicular Antibody, EV Displayed (VS-0425-YC690) (CAT#: VS-0425-YC690)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• MSR1

• Host Animal
• Rabbit

• Antibody Isotype
• IgG

• Species Reactivity
• Mouse

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Macrophage scavenger receptor 1

• Biological Process
• Endocytosis

• Molecular Function
• Receptor

• Introduction
• Enables amyloid-beta binding activity; cargo receptor activity; and low-density lipoprotein particle binding activity. Involved in several processes, including endocytosis; positive regulation of cholesterol storage; and positive regulation of macrophage derived foam cell differentiation. Acts upstream of or within establishment of localization in cell and lipoprotein transport. Located in plasma membrane. Is expressed in several structures, including alimentary system; early conceptus; limb; neural tube; and reproductive system. Human ortholog(s) of this gene implicated in Barrett's esophagus; arteriosclerosis; and prostate cancer. Orthologous to human MSR1 (macrophage scavenger receptor 1).

• Alternative Names
• MRS-A, MSR, MSR-A, SR-A, SR-AI, SR-AII, Scara1, Scvr

• Gene ID
• 20288

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