Rabbit Anti-MSR1 Recombinant Antibody (clone R48-1E-2) (CAT#: VS3-FY2120)
This R48-1E-2 recombinant monoclonal antibody that is capable of recognizing human MSR1 protein, a calculated weight of 50 kDa. It cross-reacts with mouse, rat.
The following recommendations serve as a starting point for assay optimization. The actual working concentration may vary and should be determined by the user. The R48-1E-2 is recommended for detection of target protein by western blotting (dilution range 1:500-1:1000).
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Normal Tissue
RNA Expression
Figure 1 Lung
(Macrophages
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/272/736_A_2_4.jpg
(Macrophages
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/272/736_A_2_4.jpg
Figure 2 RNA cell line category: Group enriched (BJ hTERT+, REH)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000038945-MSR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000038945-MSR1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat MSR1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R48-1E-2
- Applications
- Western Blot
- Conjugate
- Unconjugated
- MW
- The calculated weight of the target protein is approximately 50 kDa, while the observed molecular weight stands at 75kDa.
- Related Disease
- Atherosclerosis, Alzheimer's disease, and host defense
Product Property
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4), 150 mM NaCl, 50% glycerol
- Preservative
- 0.02% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Macrophage Scavenger Receptor 1; Macrophage Acetylated LDL Receptor I And II; Scavenger Receptor Class A Member 1; SCARA1; Macrophage Scavenger Receptor Types I And II; Macrophage Scavenger Receptor Type III; CD204 Antigen; SR-AIII
- Gene ID
- 4481
- UniProt ID
- P21757
- Cellular Localization
- Membrane
- Post Translation Modifications
- Glycosylation at Asn82, Asn102, Asn143, Asn184, Asn221, Asn249, and Asn267 (NX_P21757 [NX_P21757-1])
Modification sites at PhosphoSitePlus (P21757)
Glycosylation from GlyGen (P21757) 7 sites
- Protein Refseq
- XP_024302929.1; XP_054216473.1; NP_001350673.1; NP_002436.1; NP_619729.1
- Function
- Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-107 | Recombinant Rat Anti-mouse Msr1 Antibody, clone 2F8 | IP, WB | IgG |
| MOB-1113CT | Recombinant Mouse anti-Human MSR1 Monoclonal antibody (EML563) | WB | |
| FAMAB-1613CQ | Rabbit Anti-MSR1 Recombinant Antibody (clone 2F8) | IP, WB, IHC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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