Recombinant Anti-NCR3LG1 Vesicular Antibody, EV Displayed (VS-0425-YC261)
CAT#: VS-0425-YC261
The Recombinant Anti-NCR3LG1 Vesicular Antibody, EV Displayed (VS-0425-YC261) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to NCR3LG1-expressed cells or tissues. The NCR3LG1 is a protein expressed on tumor cells, activating NK cells through interactions with ligands.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24137/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24137/52704_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24137/52704_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24137/52704_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24137/52704_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24137/52704_A_4_6.jpg
Normal Tissue
Figure 7 Skin
Keratinocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24137/52704_B_7_1.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: nuclear Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24137/52704_A_9_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (HL-60, K-562)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000188211-NCR3LG1
❮
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Recombinant Antibody
- Application
- Block, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- NCR3LG1
- Host Animal
- Mouse
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein G
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Natural killer cell cytotoxicity receptor 3 ligand 1
- Introduction
- B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]
- Alternative Names
- B7-H6, DKFZp686O24166
- Gene ID
- 374383
- UniProt ID
- Q68D85
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1134CL-F(E) | Mouse Anti-NCR3LG1 Recombinant Antibody; Fab Fragment (TAB-1134CL-F(E)) | ELISA | Mouse Fab |
| TAB-1135CL-F(E) | Anti-Human NCR3LG1 Recombinant Antibody Fab Fragment (1.18) | ELISA, FC, IHC | |
| TAB-1136CL-F(E) | Mouse Anti-NCR3LG1 Recombinant Antibody; Fab Fragment (TAB-1136CL-F(E)) | ELISA, Block (partially), IP | Mouse Fab |
| TAB-1138CL-F(E) | Mouse Anti-NCR3LG1 Recombinant Antibody; Fab Fragment (TAB-1138CL-F(E)) | IP, ELISA | Mouse Fab |
| TAB-1139CL-F(E) | Mouse Anti-NCR3LG1 Recombinant Antibody; Fab Fragment (TAB-1139CL-F(E)) | ELISA, Block (partially) | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0433-YC | Human Anti-NCR3LG1 Recombinant Antibody (HPAB-M0433-YC) | FC | Human IgG |
| HPAB-M0434-YC | Human Anti-NCR3LG1 Recombinant Antibody (HPAB-M0434-YC) | FC | Human IgG |
| HPAB-M0435-YC | Human Anti-NCR3LG1 Recombinant Antibody (HPAB-M0435-YC) | FC | Human IgG |
| HPAB-M0436-YC | Human Anti-NCR3LG1 Recombinant Antibody (HPAB-M0436-YC) | FC | Human IgG |
| PABS-0151 | Human Anti-NCR3LG1 Recombinant Antibody (Clone 01JF51) | ELISA, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0433-YC-S(P) | Human Anti-NCR3LG1 Recombinant Antibody; scFv Fragment (HPAB-M0433-YC-S(P)) | FC | Human scFv |
| HPAB-M0434-YC-S(P) | Human Anti-NCR3LG1 Recombinant Antibody; scFv Fragment (HPAB-M0434-YC-S(P)) | FC | Human scFv |
| HPAB-M0435-YC-S(P) | Human Anti-NCR3LG1 Recombinant Antibody; scFv Fragment (HPAB-M0435-YC-S(P)) | FC | Human scFv |
| HPAB-M0436-YC-S(P) | Human Anti-NCR3LG1 Recombinant Antibody; scFv Fragment (HPAB-M0436-YC-S(P)) | FC | Human scFv |
| PSBS-0151 | Human Anti-NCR3LG1 Recombinant Antibody (Clone 01JF51); scFv Fragment | ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0433-YC-F(E) | Human Anti-NCR3LG1 Recombinant Antibody; Fab Fragment (HPAB-M0433-YC-F(E)) | FC | Human Fab |
| HPAB-M0434-YC-F(E) | Human Anti-NCR3LG1 Recombinant Antibody; Fab Fragment (HPAB-M0434-YC-F(E)) | FC | Human Fab |
| HPAB-M0435-YC-F(E) | Human Anti-NCR3LG1 Recombinant Antibody; Fab Fragment (HPAB-M0435-YC-F(E)) | FC | Human Fab |
| HPAB-M0436-YC-F(E) | Human Anti-NCR3LG1 Recombinant Antibody; Fab Fragment (HPAB-M0436-YC-F(E)) | FC | Human Fab |
| PFBS-0151 | Human Anti-NCR3LG1 Recombinant Antibody (Clone 01JF51); Fab Fragment | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY200 | AbPlus™ Anti-NCR3LG1 Magnetic Beads (VS-0424-XY200) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY66 | Human Anti-NCR3LG1 scFv-Fc Chimera (VS-0325-FY66) | FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC775 | CytoStream™ Rabbit Anti-NCR3LG1 Recombinant Antibody (VS13-YC775) | FC, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4719 | Anti-NCR3LG1 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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