Recombinant Anti-NCR3LG1 Vesicular Antibody, EV Displayed (VS-0425-YC261) (CAT#: VS-0425-YC261)

The Recombinant Anti-NCR3LG1 Vesicular Antibody, EV Displayed (VS-0425-YC261) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to NCR3LG1-expressed cells or tissues. The NCR3LG1 is a protein expressed on tumor cells, activating NK cells through interactions with ligands.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Recombinant Antibody

  • Application
  • Block, ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • NCR3LG1
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG1
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein G
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Natural killer cell cytotoxicity receptor 3 ligand 1
  • Introduction
  • B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]
  • Alternative Names
  • B7-H6, DKFZp686O24166

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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