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NCR3LG1

Anti-NCR3LG1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]
Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Excitatory neurons, Inhibitory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HL-60, K-562)

Interaction

Monomer. Interacts specifically with NCR3, but not with other natural killer cell-activating receptors, including NCR1, NCR2 and KLRK1.

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