Recombinant Anti-P2rx4 Vesicular Antibody, EV Displayed (VS-0425-YC287)
CAT#: VS-0425-YC287
The Recombinant Anti-P2rx4 Vesicular Antibody, EV Displayed (VS-0425-YC287) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to P2rx4-expressed cells or tissues. The P2rx4 is an ATP-gated ion channel involved in processes like vasodilation and is expressed in multiple systems, including the cardiovascular and nervous systems.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39494/85835_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39494/85835_A_7_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39494/85835_A_9_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39494/85835_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39494/85835_A_6_6.jpg
Normal Tissue
Figure 6 Placenta
Trophoblastic cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39494/85835_A_1_7.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39494/85835_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135124-P2RX4
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- P2rx4
- Host Animal
- Rat
- Antibody Isotype
- IgG2a
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Purinergic receptor P2X 4
- Biological Process
- Ion transport, Transport
- Molecular Function
- Ion channel, Ligand-gated ion channel, Receptor
- Introduction
- Enables extracellularly ATP-gated monoatomic cation channel activity. Acts upstream of or within several processes, including excitatory postsynaptic potential; nitric oxide biosynthetic process; and vasodilation. Located in apical part of cell. Is active in lysosomal membrane. Is expressed in several structures, including cardiovascular system; gut; immune system; nervous system; and viscerocranium. Orthologous to human P2RX4 (purinergic receptor P2X 4).
- Alternative Names
- P2X4; D5Ertd444e
- Gene ID
- 18438
- UniProt ID
- D3Z5U5
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Datasheet
MSDS
COA
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See other products for "P2RX4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0914CL | Human Anti-P2RX4 Recombinant Antibody (TAB-0914CL) | ELISA | Human IgG |
| TAB-0914CL-S(P) | Human Anti-P2RX4 Recombinant Antibody; scFv Fragment (TAB-0914CL-S(P)) | ELISA | Human scFv |
| TAB-0914CL-F(E) | Human Anti-P2RX4 Recombinant Antibody; Fab Fragment (TAB-0914CL-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0915CL | Rat Anti-P2rx4 Recombinant Antibody (TAB-0915CL) | ELISA | Rat IgG2a |
| TAB-0915CL-S(P) | Rat Anti-P2rx4 Recombinant Antibody; scFv Fragment (TAB-0915CL-S(P)) | ELISA | Rat scFv |
| TAB-0915CL-F(E) | Rat Anti-P2rx4 Recombinant Antibody; Fab Fragment (TAB-0915CL-F(E)) | ELISA | Rat Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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