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P2RX4
Loading...Anti-P2RX4 Products
- Human Anti-P2RX4 Recombinant Antibody (TAB-0914CL) (TAB-0914CL)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-P2RX4 Recombinant Antibody; scFv Fragment (TAB-0914CL-S(P)) (TAB-0914CL-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-P2RX4 Recombinant Antibody; Fab Fragment (TAB-0914CL-F(E)) (TAB-0914CL-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Rat Anti-P2rx4 Recombinant Antibody; Fab Fragment (TAB-0915CL-F(E)) (TAB-0915CL-F(E))
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- Species Reactivity: Mouse
- Type: Rat Fab
- Application: ELISA
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- Rat Anti-P2rx4 Recombinant Antibody; scFv Fragment (TAB-0915CL-S(P)) (TAB-0915CL-S(P))
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- Species Reactivity: Mouse
- Type: Rat scFv
- Application: ELISA
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- Rat Anti-P2rx4 Recombinant Antibody (TAB-0915CL) (TAB-0915CL)
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- Species Reactivity: Mouse
- Type: Rat IgG2a
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
Background
Enables extracellularly ATP-gated monoatomic cation channel activity. Acts upstream of or within several processes, including excitatory postsynaptic potential; nitric oxide biosynthetic process; and vasodilation. Located in apical part of cell. Is active in lysosomal membrane. Is expressed in several structures, including cardiovascular system; gut; immune system; nervous system; and viscerocranium. Orthologous to human P2RX4 (purinergic receptor P2X 4).
Protein class
FDA approved drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts, Cytotrophoblasts, Distal enterocytes, Hofbauer cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Functional P2XRs are organized as homomeric and heteromeric trimers. Interacts with P2X7 (via C-terminus); this interaction is functional only in the presence of ATP (PubMed:26456657). Interacts with AP1M2 (By similarity).
Molecular function
Ion channel, Ligand-gated ion channel, Receptor
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