Recombinant Anti-PLAUR Vesicular Antibody, EV Displayed (VS-0425-YC202)
CAT#: VS-0425-YC202
The Recombinant Anti-PLAUR Vesicular Antibody, EV Displayed (VS-0425-YC202) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to PLAUR-expressed cells or tissues. The PLAUR is the receptor for urokinase plasminogen activator, influencing extracellular matrix degradation. It binds both proprotein and mature forms and may be GPI-anchored or soluble.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73533/if_selected.jpg
Subcellular Location
Figure 2 IHC staining of human bone marrow
Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Peripheral nerve/ganglion
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_A_9_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_A_5_6.jpg
Normal Tissue
Figure 7 Bone marrow
Hematopoietic cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_B_5_4.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced.
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000011422-PLAUR
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- PLAUR
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Plasminogen activator, urokinase receptor
- Molecular Function
- Receptor
- Cellular Localization
- Plasma membrane
- Introduction
- This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types.
- Alternative Names
- CD87, UPAR, URKR
- Gene ID
- 5329
- UniProt ID
- Q03405
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Datasheet
MSDS
COA
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Lot Number:
See other products for "PLAUR"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1317z | Mouse Anti-PLAUR Recombinant Antibody (clone 13C4) | WB, FC, Neut | Mouse IgG1 |
| PABL-355 | Mouse Anti-PLAUR Recombinant Antibody (PABL-355) | WB, ELISA, FuncS | Mouse IgG1 kappa |
| PABL-356 | Mouse Anti-PLAUR Recombinant Antibody (clone 8B12) | WB, ELISA, IF, FuncS | Mouse IgG |
| MOB-0021MZ | Recombinant Mouse Anti-Mouse Plaur Antibody (clone C042M) | ELISA | Mouse antibody |
| HPAB-0616YY | Human Anti-PLAUR Recombinant Antibody (clone H5L5) | ELISA, FC, WB | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-355 | Mouse Anti-PLAUR Recombinant Antibody scFv Fragment (PSBL-355) | WB, ELISA, FuncS | Mouse scFv |
| PSBL-356 | Mouse Anti-PLAUR Recombinant Antibody (clone 8B12); scFv Fragment | WB, ELISA, IF, FuncS | Mouse scFv |
| HPAB-0175-YC-S(P) | Mouse Anti-PLAUR Recombinant Antibody (clone 7G1); scFv Fragment | ELISA, WB | Mouse scFv |
| HPAB-0616YY-S(P) | Human Anti-PLAUR Recombinant Antibody (clone H5L5); scFv Fragment | ELISA, FC, WB | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-355 | Mouse Anti-PLAUR Recombinant Antibody Fab Fragment (PFBL-355) | WB, ELISA, FuncS | Mouse Fab |
| PFBL-356 | Mouse Anti-PLAUR Recombinant Antibody (clone 8B12); Fab Fragment | WB, ELISA, IF, FuncS | Mouse Fab |
| HPAB-0175-YC-F(E) | Mouse Anti-PLAUR Recombinant Antibody (clone 7G1); Fab Fragment | ELISA, WB | Mouse Fab |
| HPAB-0616YY-F(E) | Human Anti-PLAUR Recombinant Antibody (clone H5L5); Fab Fragment | ELISA, FC, WB | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-233CQ | Human Anti-PLAUR Recombinant Antibody (TAB-233CQ) | ELISA, FC, WB | Human IgG |
| TAB-234CQ | Human Anti-PLAUR Recombinant Antibody (TAB-234CQ) | FC, IP, ELISA | Human IgG |
| TAB-235CQ | Human Anti-PLAUR Recombinant Antibody (TAB-235CQ) | ELISA, IP, FC | Human IgG |
| TAB-236CQ | Anti-Human PLAUR Recombinant Antibody | ELISA, WB | Human antibody |
| TAB-237CQ | Anti-Human PLAUR Recombinant Antibody (2.6.1) | Inhib, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1863CQ | Recombinant Rat Anti-Plaur Antibody (CBL317) | BL, CyTOF, FC, WB | IgG2a |
| NEUT-1866CQ | Recombinant Mouse Anti-PLAUR Antibody (CBL303) | BL, CyTOF, FC, WB, ELISA | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1864CQ | Recombinant Mouse Anti-PLAUR Antibody (MM0597-18L1) | WB, Neut, FC | IgG1 |
| NEUT-1865CQ | Recombinant Mouse Anti-PLAUR Antibody (CBL197) | FC, Neut, WB | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4367 | Hi-Affi™ Recombinant Rabbit Anti-PLAUR Monoclonal Antibody (SI457DS) | ELISA | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC83 | Rabbit Anti-PLAUR Antibody (VS-0924-YC83) - Cancer Stem Cell Marker | IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5462 | Anti-PLAUR Immunohistochemistry Kit | IHC |
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