Recombinant Anti-PLXDC2 Vesicular Antibody, EV Displayed (VS-0425-YC117)

CAT#: VS-0425-YC117

The Recombinant Anti-PLXDC2 Vesicular Antibody, EV Displayed (VS-0425-YC117) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to PLXDC2-expressed cells or tissues. The PLXDC2 is plexin domain-containing 2, a cell surface transmembrane protein receptor for pigment epithelium-derived factor, expressed in various tissues including the eye. The protein is expressed more in the invasive area of human colorectal cancer tissues.

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • PLXDC2
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Plexin domain containing 2
  • Cellular Localization
  • Nuclear bodies
  • Introduction
  • Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epithelium derived factor, is expressed in many tissues including the eye. Plexin domain containing protein 2 is more expressed within the invasive area of human colorectal cancer tissues.
  • Alternative Names
  • FLJ14623, TEM7R
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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