Recombinant Anti-PRPS1 Vesicular Antibody, EV Displayed (VS-0425-YC5) (CAT#: VS-0425-YC5)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• PRPS1

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Phosphoribosyl pyrophosphate synthetase 1

• Biological Process
• Nucleotide biosynthesis

• Molecular Function
• Kinase, Transferase

• Cellular Localization
• Vesicles

• Introduction
• This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome.

• Alternative Names
• CMTX5, DFN2, DFNX1, PPRibP, PRS-I

• Gene ID
• 5631

• UniProt ID
• P60891

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