PRPS1

AbPlus Formats

Anti-PRPS1 Recombinant Antibody Products

Recombinant Mouse anti-Human PRPS1 Monoclonal antibody (EML955) (MOB-1634CT)
- Species Reactivity: Human
- Application: WB
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Recombinant Mouse Anti-PRPS1 Antibody (VS-0923-FY224) (VS-0923-FY224)
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA, WB
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Recombinant Anti-PRPS1 Vesicular Antibody, EV Displayed (VS-0425-YC5) (VS-0425-YC5)
- Species Reactivity: Human
- Target: PRPS1
- Host Animal: Mouse
- Application: ELISA, FC, Cell-uptake
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For Research Use Only. Not For Clinical Use.

This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome.

Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Homodimer. The active form is probably a hexamer composed of 3 homodimers.

Molecular function

Kinase, Transferase

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