Recombinant Anti-RXFP1 Vesicular Antibody, EV Displayed (VS-0425-YC315)
CAT#: VS-0425-YC315
The Recombinant Anti-RXFP1 Vesicular Antibody, EV Displayed (VS-0425-YC315) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to RXFP1-expressed cells or tissues. The RXFP1 is a GPCR involved in reproductive processes, acting as a receptor for relaxin. Expression variations are associated with endometriosis.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human oral mucosa
Immunohistochemical staining of human oral mucosa shows moderate cytoplasmic positivity in squamous epithelial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27067/ihc_selected.jpg
Normal Tissue
Figure 2 Skin
Keratinocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Melanocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27067/60820_B_9_1.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (EFO-21, HEL, RPTEC TERT1, THP-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171509-RXFP1
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- RXFP1
- Host Animal
- Mouse
- Antibody Isotype
- IgG2a
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Relaxin family peptide receptor 1
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Introduction
- This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
- Alternative Names
- LGR7, RXFPR1
- Gene ID
- 59350
- UniProt ID
- Q9HBX9
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "RXFP1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0657CL-S(P) | Anti-Human RXFP1 Recombinant Antibody scFv Fragment (22DA6) | ELISA, FC | |
| TAB-0658CL-S(P) | Anti-Human RXFP1 Recombinant Antibody scFv Fragment (22DA7) | ELISA, FC | |
| TAB-0659CL-S(P) | Anti-Human RXFP1 Recombinant Antibody scFv Fragment (22DA17) | ELISA, FC | |
| TAB-0660CL-S(P) | Anti-Human RXFP1 Recombinant Antibody scFv Fragment (22DA22) | ELISA, FC | |
| TAB-0657CL-F(E) | Anti-Human RXFP1 Recombinant Antibody Fab Fragment (22DA6) | ELISA, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1397MZ | Recombinant Mouse Anti-Human RXFP1 Antibody | WB | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6282 | Anti-RXFP1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6283 | Anti-Mouse RXFP1 Immunohistochemistry Kit | IHC |
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