Recombinant Anti-S1PR4 Vesicular Antibody, EV Displayed (VS-0425-YC165) (CAT#: VS-0425-YC165)

The Recombinant Anti-S1PR4 Vesicular Antibody, EV Displayed (VS-0425-YC165) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to S1PR4-expressed cells or tissues. The S1PR4 is a member of the G-protein-coupled receptor family, specifically expressed in lymphoid tissue, involved in cell signaling.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
RNA Expression

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • S1PR4
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Sphingosine-1-phosphate receptor 4
  • Molecular Function
  • G-protein coupled receptor, Receptor, Transducer
  • Cellular Localization
  • Mitochondria
  • Introduction
  • This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue.
  • Alternative Names
  • EDG6

Downloads

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