Recombinant Anti-S1PR4 Vesicular Antibody, EV Displayed (VS-0425-YC165) (CAT#: VS-0425-YC165)
The Recombinant Anti-S1PR4 Vesicular Antibody, EV Displayed (VS-0425-YC165) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to S1PR4-expressed cells or tissues. The S1PR4 is a member of the G-protein-coupled receptor family, specifically expressed in lymphoid tissue, involved in cell signaling.
Specific Inquiry
Subcellular Location
RNA Expression

Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60601/1688_F7_8_cr57f3f007b34af_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60601/1688_F7_8_cr57f3f007b34af_selected.jpg

Figure 2 RNA cell line category: Cell line enhanced (HDLM-2, HL-60, NB-4, REH, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125910-S1PR4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125910-S1PR4
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- S1PR4
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Sphingosine-1-phosphate receptor 4
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Mitochondria
- Introduction
- This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue.
- Alternative Names
- EDG6
- Gene ID
- 8698
- UniProt ID
- O95977
Downloads
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Human Antibody Products
IgG Antibody Products
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-383CT | Human Anti-S1PR4 Recombinant Antibody (TAB-383CT) | ELISA, WB | Human IgG2 |
TAB-383CT-S(P) | Human Anti-S1PR4 Recombinant Antibody; scFv Fragment (TAB-383CT-S(P)) | ELISA, WB | Human scFv |
TAB-383CT-F(E) | Human Anti-S1PR4 Recombinant Antibody; Fab Fragment (TAB-383CT-F(E)) | ELISA, WB | Human Fab |
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For Research Use Only. Not For Clinical Use.
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