Recombinant Anti-S1PR4 Vesicular Antibody, EV Displayed (VS-0425-YC165)
CAT#: VS-0425-YC165
The Recombinant Anti-S1PR4 Vesicular Antibody, EV Displayed (VS-0425-YC165) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to S1PR4-expressed cells or tissues. The S1PR4 is a member of the G-protein-coupled receptor family, specifically expressed in lymphoid tissue, involved in cell signaling.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60601/1688_F7_8_cr57f3f007b34af_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (HDLM-2, HL-60, NB-4, REH, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125910-S1PR4
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- S1PR4
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Sphingosine-1-phosphate receptor 4
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Mitochondria
- Introduction
- This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue.
- Alternative Names
- EDG6
- Gene ID
- 8698
- UniProt ID
- O95977
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "S1PR4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-383CT | Human Anti-S1PR4 Recombinant Antibody (TAB-383CT) | ELISA, WB | Human IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-383CT-S(P) | Human Anti-S1PR4 Recombinant Antibody; scFv Fragment (TAB-383CT-S(P)) | ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-383CT-F(E) | Human Anti-S1PR4 Recombinant Antibody; Fab Fragment (TAB-383CT-F(E)) | ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0670F | Mouse Anti-S1PR4 Recombinant Antibody (clone 1) | WB, FC | Mouse IgG1 |
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