Recombinant Human Anti-SARS-CoV-2 S1 Antibody (clone S728-1157)
CAT#: VS-0723-XY12
This product is a broadly neutralizing antibody clone S728-1157, which targeting the receptor-binding site (RBS). It has cross-neutralization of all SARS-COV-2 dominant variants (D614G, Beta, Delta, Kappa, Mu, and Omicron BA.1/BA.2/BA.2.75/BA.4/BA.5/BL.1/XBB).
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- SARS-CoV-2 S1
- Species Reactivity
- SARS-CoV-2 (Omicron BA.1/BA.2/BA.2.75/BA.4/XBB)
- Clone
- S728-1157
- Applications
- ELISA, BLI, Neut
- Related Disease
- Coronavirus Disease 2019
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95%
- Format
- Liquid
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- ELISA: 10 μg/mL
Neutralization assay (IC50): The range of 8-300 ng/mL for BA.2.75, BL.1, BA.4, BA.5, and XBB.
Target
- Alternative Names
- Severe acute respiratory syndrome coronavirus 2 Spike S1
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Broad Neutralization Capability
This Recombinant Human Anti-SARS-CoV-2 S1 Antibody (clone S728-1157) is impressive due to its broad cross-neutralization of variants like Omicron and Delta. We used it in our neutralization assays and BLI studies, yielding robust and reproducible data.
High Affinity Binding
We tested this antibody using Biolayer Interferometry (BLI) and ELISA. It binds the SARS-CoV-2 S1 receptor-binding site with high affinity. It is an excellent reagent for research into viral receptor interactions and variant analysis.
Q&As
-
Does this antibody neutralize Omicron variants?
A: Yes, clone S728-1157 is a broadly neutralizing antibody that has shown cross-neutralization against all SARS-COV-2 dominant variants including Omicron BA.1/BA.2/BA.4/BA.5 and XBB.
-
What is the immunogen for this antibody?
A: This antibody targets the SARS-CoV-2 S1 subunit, specifically binding to the receptor-binding site (RBS), which is essential for the virus's ability to infect host cells.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Recommended Dilution Buffer
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- Product Name
Secondary Antibody
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Isotype Control
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