Recombinant Anti-SCN2B Vesicular Antibody, EV Displayed (VS-0425-YC124) (CAT#: VS-0425-YC124)
The Recombinant Anti-SCN2B Vesicular Antibody, EV Displayed (VS-0425-YC124) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SCN2B-expressed cells or tissues. The SCN2B is the beta 2 subunit of the type II voltage-gated sodium channel. This encoded protein is involved in cell-cell adhesion and migration, with defects potentially causing Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome.
Specific Inquiry
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SCN2B
- Host Animal
- Human
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Sodium voltage-gated channel beta subunit 2
- Biological Process
- Ion transport, Sodium transport, Transport
- Molecular Function
- Ion channel, Sodium channel, Voltage-gated channel
- Introduction
- The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome.
- Gene ID
- 6327
- UniProt ID
- O60939
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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