Recombinant Anti-SSTR2 Vesicular Antibody, EV Displayed (VS-0425-YC19) (CAT#: VS-0425-YC19)
The Recombinant Anti-SSTR2 Vesicular Antibody, EV Displayed (VS-0425-YC19) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SSTR2-expressed cells or tissues. The SSTR2 is a receptor belonging to the G protein-coupled receptor family, mediating inhibitory effects of somatostatin on hormone release, with high expression in the cerebrum and kidney.

(Immunofluorescent staining of human cell line A-431 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7264/39_A12_2_selected.jpg

(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7264/19238_B_7_5.jpg

(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7264/19238_A_8_3.jpg

(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7264/19238_A_7_4.jpg

(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7264/19238_A_4_6.jpg

(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000180616-SSTR2
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SSTR2
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Somatostatin receptor 2
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Cytosol, Nucleoplasm
- Introduction
- Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney.
- Gene ID
- 6752
- UniProt ID
- P30874
Downloads
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See other products for "SSTR2"
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-179CQ | Mouse Anti-Human SSTR2 Antibody | ELISA, WB, IF, IP, IHC-P | Mouse IgG1, κ |
ZG-0578U | Rabbit Anti-SSTR2 Recombinant Antibody (clone 1C3) | ELISA, IHC | Rabbit IgG |
VS4-CJ126 | Recombinant Human Anti-SSTR2 Antibody (clone 7A9) | ELISA, FC | Human IgG1 |
VS-0723-WK27 | Human Anti-SSTR2 Recombinant Antibody (clone Tidutamab) | ELISA, FC | Chimeric (mouse/human) IgG1 |
VS-0723-WK131 | Human Anti-SSTR2 Recombinant Antibody (VS-0723-WK131) | FC | Chimeric (rabbit/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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