Recombinant Anti-STX1A Vesicular Antibody, EV Displayed (VS-0425-YC661)
CAT#: VS-0425-YC661
The Recombinant Anti-STX1A Vesicular Antibody, EV Displayed (VS-0425-YC661) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to STX1A-expressed cells or tissues. STX1A is a syntaxin family member involved in synaptic vesicle docking to the presynaptic membrane. It plays a role in calcium-dependent synaptic exocytosis, interacting with synaptotagmin and ion channels.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (SCLC-21H, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000106089-STX1A/subcellular
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Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- STX1A
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Syntaxin 1A
- Biological Process
- Exocytosis, Neurotransmitter transport, Transport
- Cellular Localization
- Vesicles, Nuclear membrane
- Introduction
- This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis.
- Alternative Names
- HPC-1, p35-1, STX1
- Gene ID
- 6804
- UniProt ID
- Q16623
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Datasheet
MSDS
COA
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See other products for "STX1A"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2912z | Mouse Anti-STX1A Recombinant Antibody (clone 38D10) | WB, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3450 | Hi-Affi™ Recombinant Rabbit Anti-STX1A Monoclonal Antibody (DS3450AB) | IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0040LY | Human Anti-STX1A Recombinant Antibody (clone 13C4) | WB, Inhib | Humanized IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0040LY-S(P) | Human Anti-STX1A Recombinant Antibody (clone 13C4); scfv Fragment | WB | Humanized scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0040LY-F(E) | Human Anti-STX1A Recombinant Antibody (clone 13C4); Fab Fragment | WB | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0223-WK76 | Rabbit Anti-STX1A Recombinant Antibody (VS-0223-WK76) | WB, IP, ICC, IHC, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC1124 | CytoStream™ Rabbit Anti-STX1A Recombinant Antibody (VS13-YC1124) | WB, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7000 | Anti-STX1A Immunohistochemistry Kit | IHC |
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