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  • Recombinant Mouse Anti-TBL1Y Antibody (VS4-CJ133)

Recombinant Mouse Anti-TBL1Y Antibody (VS4-CJ133) (CAT#: VS4-CJ133)

This mouse anti-TBL1Y antibody is a product that recognizes human, mouse, porcine, rat, dog TBL1Y. The immunogen of this antibody is recombinant full length protein (522aa) of human TBL1Y. The mAb has been tested for use in ELISA, Western Blot (1:500-1:5000), Immunocytochemistry (1:50-1:200).


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Subcellular Location
Figure 1 IF staining of human cell line RT4
Figure 1 IF staining of human cell line RT4
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50857/1943_F10_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human prostate
Figure 2 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows strong nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60073/ihc_selected.jpg
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60073/134063_B_7_5.jpg
Figure 4 Colon
Figure 4 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60073/134063_A_8_3.jpg
Figure 5 Liver
Figure 5 Liver
(Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60073/134063_A_9_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60073/134063_A_9_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: nuclear Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60073/134063_A_6_6.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60073/134063_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enriched (U-698)
Figure 9 RNA cell line category: Cell line enriched (U-698)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000092377-TBL1Y

Specifications

  • Immunogen
  • Recombinant full length protein (522aa) of human TBL1Y.
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2b
  • Specificity
  • Human, Mouse, Porcine, Rat, Dog TBL1Y
  • Species Reactivity
  • Human, Mouse, Porcine, Rat, Dog
  • Applications
  • ELISA, WB, ICC
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Affinity purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Buffer
  • 50% Glycerol, 0.1M Tris-Glycine (150 mM NaCl), pH 7.4.
  • Preservative
  • 0.2% Sodium Azide
  • Storage
  • Store at -20°C or -80°C upon receipt. Avoid repeated freeze.

Applications

  • Application Notes
  • This antibody has been tested for use in ELISA, Western Blot (1:500-1:5000), Immunocytochemistry (1:50-1:200).

Target

  • Alternative Names
  • TBL1; DFNY2
  • Long Name
  • Transducin beta like 1 Y-linked
  • Sequence Similarities
  • Belongs to the WD repeat EBI family.
  • Cellular Localization
  • Nucleus
  • Function
  • F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange (By similarity).

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "TBL1Y"

Recombinant Antibody

CAT Product Name Application Type
MOB-1418CT Recombinant Mouse anti-Human TBL1Y Monoclonal antibody (5I3-E6-F0) ELISA, WB
VS3-CJ13 Mouse Anti-TBL1Y Recombinant Antibody (VS3-CJ13) WB, ELISA Mouse IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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