Recombinant Anti-TENM4 Vesicular Antibody, EV Displayed (VS-0425-YC112)
CAT#: VS-0425-YC112
The Recombinant Anti-TENM4 Vesicular Antibody, EV Displayed (VS-0425-YC112) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TENM4-expressed cells or tissues. The TENM4 is a protein that plays a role in establishing proper neuronal connectivity during development. Defects in this gene have been associated with hereditary essential tremor-5.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human cerebral cortex
Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in astrocytes.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19521/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human cerebral cortex
Immunohistochemical staining of human cerebral cortex shows moderate cytoplasmic positivity in glial cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65961/160543_B_7_5_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65961/160543_B_7_5.jpg
Normal Tissue
Figure 4 Caudate
Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65961/160543_B_8_7.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HSkMC, hTERT-RPE1, PC-3, REH, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000149256-TENM4
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TENM4
- Host Animal
- Human
- Antibody Isotype
- IgG2 kappa
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Teneurin transmembrane protein 4
- Biological Process
- Differentiation
- Molecular Function
- Developmental protein
- Introduction
- The protein encoded by this gene plays a role in establishing proper neuronal connectivity during development. Defects in this gene have been associated with hereditary essential tremor-5.
- Alternative Names
- DOC4, KIAA1302, ODZ4, Ten-M4, TEN4
- Gene ID
- 26011
- UniProt ID
- Q6N022
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-595CT | Anti-Human Ten-M4 Recombinant Antibody (1.58) | ELISA, FC | Human antibody |
| TAB-596CT | Anti-Human Ten-M4 Recombinant Antibody (2.36) | ELISA, FC | Human antibody |
| TAB-597CT | Anti-Human Ten-M4 Recombinant Antibody (1.48) | ELISA, FC | Human antibody |
| TAB-595CT-S(P) | Anti-Human Ten-M4 Recombinant Antibody scFv Fragment (1.58) | ELISA, FC | Human antibody |
| TAB-596CT-S(P) | Anti-Human Ten-M4 Recombinant Antibody scFv Fragment (2.36) | ELISA, FC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0307CQ | Human Anti-TENM4 Recombinant Antibody (clone mAb 1.20) | ELISA, Inhib, FuncS | Human IgG2, κ |
| VS-0723-WK64 | Human Anti-TENM4 Recombinant Antibody (VS-0723-WK64) | FC | Chimeric (rabbit/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0307CQ-F(E) | Human Anti-TENM4 Recombinant Antibody (clone mAb 1.20); Fab Fragment | ELISA, Neut, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0307CQ-S(P) | Human Anti-TENM4 Recombinant Antibody (clone mAb 1.20); scFv Fragment | ELISA, Neut, FuncS | Human scFv |
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