Recombinant Anti-TENM4 Vesicular Antibody, EV Displayed (VS-0425-YC112) (CAT#: VS-0425-YC112)
The Recombinant Anti-TENM4 Vesicular Antibody, EV Displayed (VS-0425-YC112) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TENM4-expressed cells or tissues. The TENM4 is a protein that plays a role in establishing proper neuronal connectivity during development. Defects in this gene have been associated with hereditary essential tremor-5.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in astrocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19521/ihc_selected.jpg
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in astrocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19521/ihc_selected.jpg
Figure 2 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows moderate cytoplasmic positivity in glial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65961/160543_B_7_5_selected.jpg
(Immunohistochemical staining of human cerebral cortex shows moderate cytoplasmic positivity in glial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65961/160543_B_7_5_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65961/160543_B_7_5.jpg
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65961/160543_B_7_5.jpg
Figure 4 Caudate
(Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65961/160543_B_8_7.jpg
(Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65961/160543_B_8_7.jpg
Figure 5 RNA cell line category: Cell line enhanced (HSkMC, hTERT-RPE1, PC-3, REH, SH-SY5Y)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000149256-TENM4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000149256-TENM4
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TENM4
- Host Animal
- Human
- Antibody Isotype
- IgG2 kappa
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Teneurin transmembrane protein 4
- Biological Process
- Differentiation
- Molecular Function
- Developmental protein
- Introduction
- The protein encoded by this gene plays a role in establishing proper neuronal connectivity during development. Defects in this gene have been associated with hereditary essential tremor-5.
- Alternative Names
- DOC4, KIAA1302, ODZ4, Ten-M4, TEN4
- Gene ID
- 26011
- UniProt ID
- Q6N022
Downloads
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Human Antibody Products
IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-595CT | Anti-Human Ten-M4 Recombinant Antibody (1.58) | ELISA, FC | Human antibody |
| TAB-596CT | Anti-Human Ten-M4 Recombinant Antibody (2.36) | ELISA, FC | Human antibody |
| TAB-597CT | Anti-Human Ten-M4 Recombinant Antibody (1.48) | ELISA, FC | Human antibody |
| TAB-595CT-S(P) | Anti-Human Ten-M4 Recombinant Antibody scFv Fragment (1.58) | ELISA, FC | Human antibody |
| TAB-596CT-S(P) | Anti-Human Ten-M4 Recombinant Antibody scFv Fragment (2.36) | ELISA, FC | Human antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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