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TENM4

The protein encoded by this gene plays a role in establishing proper neuronal connectivity during development. Defects in this gene have been associated with hereditary essential tremor-5.
Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Excitatory neurons, Inhibitory neurons, Astrocytes, Microglial cells, Early spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HSkMC, hTERT-RPE1, PC-3, REH, SH-SY5Y)

Interaction

Homodimer; disulfide-linked (Probable). May also form heterodimer with either TENM1 or TENM2 or TENM3 (By similarity).

Molecular function

Developmental protein

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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