Recombinant Anti-TTYH1 Vesicular Antibody, EV Displayed (VS-0425-YC477) (CAT#: VS-0425-YC477)
The Recombinant Anti-TTYH1 Vesicular Antibody, EV Displayed (VS-0425-YC477) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TTYH1-expressed cells or tissues. The TTYH1 is a member of the Tweety family, with disruptions linked to embryonic lethality.

(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5725/1947_G9_1_selected.jpg

(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23617/71436_B_7_5.jpg

(G L U G L U Processes in molecular layer Staining: High Intensity: Strong Purkinje cells - cytoplasm/membrane Staining: Medium Intensity: Moderate Synaptic glomeruli - capsule Staining: Low Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23617/71436_B_8_8.jpg

(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23617/71436_A_9_5.jpg

(Elongated or late spermatids Staining: Low Intensity: Moderate Quantity: <25% Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Pachytene spermatocytes Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23617/71436_A_6_6.jpg

(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167614-TTYH1
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TTYH1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Tweety family member 1
- Biological Process
- Cell adhesion, Ion transport, Transport
- Molecular Function
- Chloride channel, Ion channel
- Cellular Localization
- Nucleoplasm, Plasma membrane
- Introduction
- This gene encodes a member of the Tweety family of membrane proteins. Members of this family contain five predicted transmembrane regions that are arranged in a characteristic pattern. In mouse, the protein is predominantly localized to the endoplasmic reticulum and displays calcium binding activity. Targeted knock out of this gene results in early embryonic lethality prior to the blastocyst stage.
- Alternative Names
- tty; TTY1; mTTY1; 4930459B04Rik; 6330408P11Rik
- Gene ID
- 57776
- UniProt ID
- Q9D3A9
Downloads
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See other products for "TTYH1"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2117CT | Recombinant Mouse anti-Human TTYH1 Monoclonal antibody (EML1758) | WB | |
HPAB-M0323-YC | Mouse Anti-TTYH1 Recombinant Antibody (clone Ttyh1-11) | WB, IF, IHC | Mouse IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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