Recombinant Anti-UPK2 Vesicular Antibody, EV Displayed (VS-0425-YC672) (CAT#: VS-0425-YC672)
The Recombinant Anti-UPK2 Vesicular Antibody, EV Displayed (VS-0425-YC672) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to UPK2-expressed cells or tissues. UPK2 is a urothelium-specific protein forming apical plaques, expressed in bladder cancer patients with transitional cell carcinomas.

(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43312/96079_A_8_5.jpg

(Urothelial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43312/96079_A_6_5.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110375-UPK2
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- UPK2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Uroplakin 2
- Introduction
- This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009]
- Alternative Names
- MGC138598, UP2, UPII
- Gene ID
- 7379
- UniProt ID
- O00526
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "UPK2"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-3648z | Mouse Anti-UPK2 Recombinant Antibody (clone 41H9) | WB, IHC | Mouse IgG1 |
HPAB-0028CQ | Mouse Anti-UPK2 Recombinant Antibody (HPAB-0028CQ) | ELISA, WB, IHC | Mouse IgG1, κ |
VS13-YC1207 | Rabbit Anti-UPK2 Recombinant Antibody (VS13-YC1207) | WB, IHC-P, IHC-Fr, ICC, IF, ELISA | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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