Recombinant Anti-UPK2 Vesicular Antibody, EV Displayed (VS-0425-YC672)
CAT#: VS-0425-YC672
The Recombinant Anti-UPK2 Vesicular Antibody, EV Displayed (VS-0425-YC672) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to UPK2-expressed cells or tissues. UPK2 is a urothelium-specific protein forming apical plaques, expressed in bladder cancer patients with transitional cell carcinomas.
Gene Expression
Normal Tissue
Figure 1 Kidney
Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43312/96079_A_8_5.jpg
Normal Tissue
Figure 2 High expression in urinary bladder
Urothelial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43312/96079_A_6_5.jpg
RNA Expression
Figure 3 RNA cell line category: Group enriched (MCF7, RT4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110375-UPK2
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- UPK2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Uroplakin 2
- Introduction
- This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009]
- Alternative Names
- MGC138598, UP2, UPII
- Gene ID
- 7379
- UniProt ID
- O00526
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "UPK2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3648z | Mouse Anti-UPK2 Recombinant Antibody (clone 41H9) | WB, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0028CQ | Mouse Anti-UPK2 Recombinant Antibody (HPAB-0028CQ) | ELISA, WB, IHC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0028CQ-S(P) | Mouse Anti-UPK2 Recombinant Antibody; scFv Fragment (HPAB-0028CQ-S(P)) | ELISA, WB, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0028CQ-F(E) | Mouse Anti-UPK2 Recombinant Antibody; Fab Fragment (HPAB-0028CQ-F(E)) | ELISA, WB, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC1207 | Rabbit Anti-UPK2 Recombinant Antibody (VS13-YC1207) | WB, IHC-P, IHC-Fr, ICC, IF, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7757 | Anti-UPK2 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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