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ACOX1
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Anti-ACOX1 Products
- Mouse Anti-ACOX1 Recombinant Antibody (VS3-FY2618) (VS3-FY2618)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, ICC
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- Anti-ACOX1 Immunohistochemistry Kit (VS-0525-XY85)
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- Species Reactivity: Human
- Target: ACOX1
- Application: IHC
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- Chicken Anti-ACOX1 Polyclonal IgY (BRD-0014MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Hepatocytes, Proximal enterocytes, Distal enterocytes)
Immune cell specificity
Group enriched (neutrophil, basophil)
Cell line specificity
Cell line enhanced (BEWO, RT4)
Interaction
Homodimer (PubMed:32169171). Interacts with LONP2 (PubMed:18281296).
Molecular function
Oxidoreductase
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