Mouse Anti-ACOX1 Recombinant Antibody (VS3-FY2618) (CAT#: VS3-FY2618)
This outstanding mouse recombinant monoclonal antibody demonstrates a high level of efficacy in its binding to ACOX1. The calculated molecular weight of the antigen is 74.4 kDa. It exhibits cross-reactivity with human. The antibody can be utilized for detection of ACOX1 by Western Blot, Immunohistochemistry, Immunocytochemistry.
Specific Inquiry
Custom Production
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & peroxisomes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21195/395_B1_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & peroxisomes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21195/395_B1_1_selected.jpg
Figure 2 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21195/49200_A_5_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21195/49200_A_5_6.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21195/49200_B_9_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21195/49200_B_9_5.jpg
Figure 4 Liver
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21195/49200_A_7_4.jpg
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21195/49200_A_7_4.jpg
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21195/49200_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21195/49200_A_8_5.jpg
Figure 6 RNA cell line category: Cell line enhanced (BEWO, RT4)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000161533-ACOX1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000161533-ACOX1
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Acyl-CoA oxidase 1 of human
- Species Reactivity
- Human
- Applications
- WB, IHC, ICC
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 74.4 kDa.
- Related Disease
- Cancer
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/200
Immunocytochemistry: 1/10-1/50
Target
- Alternative Names
- Acyl-CoA Oxidase 1; Palmitoyl-CoA Oxidase; Acyl-Coenzyme A Oxidase 1, Palmitoyl; Straight-Chain Acyl-CoA Oxidase; Acyl-CoA Oxidase 1, Palmitoyl; EC 1.3.3.6; ACOX
- Gene ID
- 51
- UniProt ID
- Q15067
- Sequence Similarities
- Belongs to the acyl-CoA oxidase family.
- Cellular Localization
- Peroxisome
- Post Translation Modifications
- Modification sites at PhosphoSitePlus
Modification sites at neXtProt
Glycosylation from GlyGen 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_047292138.1; XP_047292139.1; XP_054172311.1; XP_054172312.1; NP_001171968.1
- Function
- Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids (PubMed:7876265, 15060085, 17458872, 17603022, 32169171, 33234382).
Catalyzes the desaturation of fatty acyl-CoAs such as palmitoyl-CoA (hexadecanoyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs) such as (2E)-hexadecenoyl-CoA, and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)).
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0014MZ | Chicken Anti-ACOX1 Polyclonal IgY | WB | Chicken antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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