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ACP5

This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate.
Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Hepatic stellate cells, Hofbauer cells, Macrophages, Proximal tubular cells)

Immune cell specificity

Immune cell enhanced (memory B-cell)

Cell line specificity

Cell line enhanced (BEWO, K-562, RPMI-8226, SK-MEL-30, U-138 MG)

Interaction

Exists either as monomer or, after proteolytic processing, as a dimer of two chains linked by disulfide bond(s).

Molecular function

Hydrolase

More Types Infomation

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