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AKAP3
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, IF, FC
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- Anti-AKAP3 Immunohistochemistry Kit (VS-0525-XY264)
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- Species Reactivity: Human
- Target: AKAP3
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The encoded protein is reported to participate in protein-protein interactions with the R-subunit of the protein kinase A as well as sperm-associated proteins. This protein is expressed in spermatozoa and localized to the acrosomal region of the sperm head as well as the length of the principal piece. It may function as a regulator of motility, capacitation, and the acrosome reaction.
Predicted location
Intracellular
Single cell type specificity
Group enriched (Early spermatids, Late spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (JURKAT, NTERA-2)
Interaction
Interacts with ROPN1 AND ROPN1L. Interacts with QRICH2 (PubMed:30683861).
More Types Infomation
Related Signaling Pathways
cAMP Signaling Pathway